Sleep duration and risk of cancer in the Mexican American Mano-a-Mano Cohort.
Cancer risk
Mexican Americans
Sleep duration
Journal
Sleep health
ISSN: 2352-7226
Titre abrégé: Sleep Health
Pays: United States
ID NLM: 101656808
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
21
05
2018
revised:
02
08
2018
accepted:
11
09
2018
entrez:
24
1
2019
pubmed:
24
1
2019
medline:
19
4
2019
Statut:
ppublish
Résumé
To date, no study has investigated the association of sleep duration with cancer risk in Mexican Americans. Using data from the Mano-A-Mano Mexican American Cohort study, we analyzed the relationship between sleep duration and overall cancer risk among Mexican Americans. Of 10,802 subjects included in this study, 429 developed cancer during follow-up. Compared with study participants sleeping 8-9 hours per night, those sleeping less than 6 hours per night had significantly increased risk of overall cancer in both univariate and multivariate Cox regression analyses. After adjusting for social-demographic and lifestyle variables, sleeping less than 6 hours per night was associated with a 1.37-fold increased risk of overall cancer (hazard ratio = 1.37, 95% confidence interval: 1.01-1.97). In breast cancer alone, sleeping less than 6 hours per night was associated with a 1.86-fold increased risk of breast cancer (hazard ratio = 1.86, 95% confidence interval: 1.01-3.45) after adjustment for birthplace and language acculturation. In further stratified analysis, significant associations between sleeping less than 6 hours per night and overall cancer risk were evident among overweight participants, former drinkers, those with medium or high levels of physical activity, those married or living together, and those who had less than 2 hours of sitting time per day. In addition, increased cancer risk associated with long sleep duration (at least 9 hours per night) was observed among overweight participants and those with medium or high levels of physical activity. Our results provide evidence to link sleep duration with cancer risk among Mexican Americans.
Sections du résumé
BACKGROUND
To date, no study has investigated the association of sleep duration with cancer risk in Mexican Americans.
ANALYSIS
Using data from the Mano-A-Mano Mexican American Cohort study, we analyzed the relationship between sleep duration and overall cancer risk among Mexican Americans.
RESULTS
Of 10,802 subjects included in this study, 429 developed cancer during follow-up. Compared with study participants sleeping 8-9 hours per night, those sleeping less than 6 hours per night had significantly increased risk of overall cancer in both univariate and multivariate Cox regression analyses. After adjusting for social-demographic and lifestyle variables, sleeping less than 6 hours per night was associated with a 1.37-fold increased risk of overall cancer (hazard ratio = 1.37, 95% confidence interval: 1.01-1.97). In breast cancer alone, sleeping less than 6 hours per night was associated with a 1.86-fold increased risk of breast cancer (hazard ratio = 1.86, 95% confidence interval: 1.01-3.45) after adjustment for birthplace and language acculturation. In further stratified analysis, significant associations between sleeping less than 6 hours per night and overall cancer risk were evident among overweight participants, former drinkers, those with medium or high levels of physical activity, those married or living together, and those who had less than 2 hours of sitting time per day. In addition, increased cancer risk associated with long sleep duration (at least 9 hours per night) was observed among overweight participants and those with medium or high levels of physical activity.
CONCLUSION
Our results provide evidence to link sleep duration with cancer risk among Mexican Americans.
Identifiants
pubmed: 30670171
pii: S2352-7218(18)30171-2
doi: 10.1016/j.sleh.2018.09.004
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
78-83Informations de copyright
Copyright © 2018 National Sleep Foundation. All rights reserved.