Evaluating the predictive capabilities of haematoma expansion scores in patients with acute intracerebral haemorrhage: protocol for a scoping review.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
21 01 2019
Historique:
entrez: 24 1 2019
pubmed: 24 1 2019
medline: 20 2 2020
Statut: epublish

Résumé

Patients presenting with acute intracerebral haemorrhage are at a high risk of exhibiting haematoma expansion, a phenomenon that can significantly worsen long-term functioning. Numerous clinical and radiological factors are associated with expansion. In a bid to better select patients at increased risk of expanding, these factors have been collated together into clinical scores. Several clinical scores have been developed, but comparisons of diagnostic potential between these scores are limited and the frequency of use in clinical trial enrolment is unknown. To perform a scoping review of haematoma expansion scores and explore numerous factors such as the methodology of development and diagnostic capabilities. MEDLINE, PubMed, EMBASE, CENTRAL and ClinicalTrials.gov will be searched with assistance from an experienced information specialist. Eligible studies will involve adults presenting with spontaneous intracerebral haemorrhage who received baseline assessments, follow-up imaging and risk stratification through a haematoma expansion score. Reviewers will independently extract data from the included studies and will collect data on patient demographics and medical history, details on score development, diagnostic capabilities and usage proportions. Analysis of extracted data will focus on comparing the predictive capability of each score and similarities/differences in score development. The exact analysis technique will be dictated on the type of data extracted. Formal ethics is not required as primary data will not be collected. The findings of this study will be disseminated through conference presentations and peer-reviewed publications.

Identifiants

pubmed: 30670520
pii: bmjopen-2018-024744
doi: 10.1136/bmjopen-2018-024744
pmc: PMC6347899
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e024744

Informations de copyright

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Vignan Yogendrakumar (V)

Ottawa Stroke Program, The Ottawa Hospital: Division of Neurology, University of Ottawa, Ottawa, Ontario, Canada.

Margaret Moores (M)

Ottawa Stroke Program, The Ottawa Hospital: Division of Neurology, University of Ottawa, Ottawa, Ontario, Canada.

Lindsey Sikora (L)

Health Sciences Library, University of Ottawa, Ottawa, Ontario, Canada.

Tim Ramsay (T)

Ottawa Methods Center, Ottawa Hospital Research Institute, University of Ottawa School of Epidemiology, Public Health and Preventative Medicine, Ottawa, Ontario, Canada.

Dean A Fergusson (DA)

Ottawa Methods Center, Ottawa Hospital Research Institute, University of Ottawa School of Epidemiology, Public Health and Preventative Medicine, Ottawa, Ontario, Canada.

Dar Dowlatshahi (D)

Ottawa Stroke Program, The Ottawa Hospital: Division of Neurology, University of Ottawa, Ottawa, Ontario, Canada.

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Classifications MeSH