Detection of

Calreticulin Jak2 MPL Mutation Myelofibrosis Myeloproliferative Diseases Thrombocythemia

Journal

Mediterranean journal of hematology and infectious diseases
ISSN: 2035-3006
Titre abrégé: Mediterr J Hematol Infect Dis
Pays: Italy
ID NLM: 101530512

Informations de publication

Date de publication:
2019
Historique:
received: 30 08 2018
accepted: 14 12 2018
entrez: 24 1 2019
pubmed: 24 1 2019
medline: 24 1 2019
Statut: epublish

Résumé

Somatic mutations in the calreticulin gene ( MPN patient samples were collected from different clinical units and screened for Using this protocol we screened 173 MPN, Overall, our method could rapidly and cost-effectively detect the mutation status in a representative cohort of Greek patients; the mutation make-up in our group was not different from what has been published for other national groups.

Sections du résumé

BACKGROUND AND OBJECTIVES OBJECTIVE
Somatic mutations in the calreticulin gene (
METHODS METHODS
MPN patient samples were collected from different clinical units and screened for
RESULTS RESULTS
Using this protocol we screened 173 MPN,
CONCLUSIONS CONCLUSIONS
Overall, our method could rapidly and cost-effectively detect the mutation status in a representative cohort of Greek patients; the mutation make-up in our group was not different from what has been published for other national groups.

Identifiants

pubmed: 30671215
doi: 10.4084/MJHID.2019.009
pii: mjhid-11-1-e2019009
pmc: PMC6328041
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e2019009

Déclaration de conflit d'intérêts

Competing interests: The authors have declared that no competing interests exist.

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Auteurs

Andreas Giannopoulos (A)

Haematology Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece.

Niki Rougkala (N)

Haematology Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece.
1st Department of Internal Medicine, Laikon Hospital, School of Medicine, University of Athens, Athens, Greece.

Theodoros Loupis (T)

Haematology Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece.

Marina Mantzourani (M)

1st Department of Internal Medicine, Laikon Hospital, School of Medicine, University of Athens, Athens, Greece.

Nora-Athina Viniou (NA)

1st Department of Internal Medicine, Laikon Hospital, School of Medicine, University of Athens, Athens, Greece.

Eleni Variami (E)

1st Department of Internal Medicine, Laikon Hospital, School of Medicine, University of Athens, Athens, Greece.

Theodoros P Vassilakopoulos (TP)

Department of Haematology and Bone Marrow Transplantation, Laikon Hospital, School of Medicine, University of Athens, Athens, Greece.

George Dryllis (G)

Haematology Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece.
Department of Haematology and Bone Marrow Transplantation, Laikon Hospital, School of Medicine, University of Athens, Athens, Greece.

Ioannis Kotsianidis (I)

Department of Haematology, Democritus University of Thrace, Medical School, Alexandroupolis, Greece.

Theodora Gougopoulou (T)

Haematology Clinic, Department of Internal Medicine, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.

Marianna Politou (M)

Laboratory of Haematology and Blood Transfusion Unit, Aretaieion Hospital, School of Medicine, University of Athens, Athens, Greece.

Kostas Konstantopoulos (K)

Department of Haematology and Bone Marrow Transplantation, Laikon Hospital, School of Medicine, University of Athens, Athens, Greece.

George Vassilopoulos (G)

Haematology Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece.
Department of Haematology, University of Thessaly Medical School, Larissa, Greece.

Classifications MeSH