Macular toxicity after short-term hydroxychloroquine therapy.
Adult
Antirheumatic Agents
/ adverse effects
Arthritis, Rheumatoid
/ drug therapy
Electroretinography
Female
Fluorescein Angiography
Follow-Up Studies
Fundus Oculi
Humans
Hydroxychloroquine
/ adverse effects
Macula Lutea
/ diagnostic imaging
Retinal Diseases
/ chemically induced
Tomography, Optical Coherence
Visual Acuity
Visual Fields
Bull's eye
hydroxychloroquine therapy
Journal
Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
entrez:
24
1
2019
pubmed:
24
1
2019
medline:
14
6
2019
Statut:
ppublish
Résumé
We report an unusual case of hydroxychloroquine (HCQ) toxicity after only 2 months of starting the treatment. A 42-year-old woman presented with visual impairment. Her visual acuity was 20/20 in the right eye and 20/25 in the left eye. Ophthalmologic examination revealed a bull's eye pattern in both eyes which was more prominent in the left eye. She had received HCQ therapy (400 mg/day) for 1 month, and had been taking 200 mg/day for 1 month for the treatment of rheumatoid arthritis. HCQ macular toxicity is rarely seen in short-term use, before 5 years, and to our knowledge, there is only one other case reported in the literature.
Identifiants
pubmed: 30672499
pii: IndianJOphthalmol_2019_67_2_289_250680
doi: 10.4103/ijo.IJO_732_18
pmc: PMC6376838
doi:
Substances chimiques
Antirheumatic Agents
0
Hydroxychloroquine
4QWG6N8QKH
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
289-292Déclaration de conflit d'intérêts
None
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