Quantitative analysis of image metrics for reduced and standard dose pediatric


Journal

The British journal of radiology
ISSN: 1748-880X
Titre abrégé: Br J Radiol
Pays: England
ID NLM: 0373125

Informations de publication

Date de publication:
Mar 2019
Historique:
pubmed: 24 1 2019
medline: 5 3 2019
entrez: 24 1 2019
Statut: ppublish

Résumé

The study performs a comprehensive analysis of image metrics to objectively support the reduction of injected activity in pediatric oncology 21 PET/MRI examinations performed on a 3-Tesla Biograph mMR scanner were analyzed. Tracer activity reduction was stimulated by decreasing the count statistics of the original list-mode data (3 MBq kg SUVmax and SUVmean increased more than 5% only in 0.6 MBq kg Results about the stability of image metrics beyond the semi-quantitative SUV parameters and subjective analysis, rigorously proves the feasibility of the reduction of injected activity to 1.5 MBqkg This is the first report on the quantitative evaluation of the effect of activity reduction on image quality in pediatric PET/MR. The findings offer objective corroboration to the feasibility of a significant dose reduction without consequences on clinical image reading and tumor burden metrics.

Identifiants

pubmed: 30673306
doi: 10.1259/bjr.20180438
pmc: PMC6541180
doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Clinical Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20180438

Références

AJR Am J Roentgenol. 2001 Feb;176(2):289-96
pubmed: 11159059
Clin Positron Imaging. 1999 May;2(3):159-171
pubmed: 14516540
J Pediatr Hematol Oncol. 2006 May;28(5):300-6
pubmed: 16772881
Pediatrics. 2007 Sep;120(3):677-82
pubmed: 17766543
Eur J Nucl Med Mol Imaging. 2008 Aug;35(8):1581-8
pubmed: 18536914
Nucl Med Commun. 2010 Mar;31(3):254-9
pubmed: 20032801
Eur J Radiol. 2010 Sep;75(3):329-35
pubmed: 20576385
Q J Nucl Med Mol Imaging. 2010 Aug;54(4):401-10
pubmed: 20823808
J Nucl Med. 2011 Jul;52(7):1028-34
pubmed: 21680684
Clin Nucl Med. 2011 Aug;36(8):672-7
pubmed: 21716019
Pediatr Radiol. 2011 Sep;41 Suppl 2:509-13
pubmed: 21847731
Eur J Nucl Med Mol Imaging. 2012 Jan;39(1):27-38
pubmed: 21946983
Eur Radiol. 2012 Sep;22(9):1946-54
pubmed: 22538627
Radiology. 2012 Aug;264(2):559-66
pubmed: 22692034
J Nucl Med. 2012 Sep;53(9):1345-51
pubmed: 22797376
Nucl Med Commun. 2012 Sep;33(9):974-81
pubmed: 22811258
Cancer. 2013 Mar 15;119(6):1195-202
pubmed: 23212736
Pediatr Radiol. 2013 Jul;43(7):860-75
pubmed: 23306377
Pediatr Radiol. 2013 Apr;43(4):406-17
pubmed: 23525767
JAMA Pediatr. 2013 Aug 1;167(8):700-7
pubmed: 23754213
Radiology. 2014 Oct;273(1):220-31
pubmed: 24877983
Eur J Nucl Med Mol Imaging. 2014 Nov;41(11):2158-60
pubmed: 24993455
Eur J Nucl Med Mol Imaging. 2015 Feb;42(2):328-54
pubmed: 25452219
J Nucl Med. 2014 Dec;55(12):1998-2002
pubmed: 25453048
Nucl Med Commun. 2015 Jul;36(7):728-37
pubmed: 25757197
Acta Radiol Open. 2015 Jan 29;4(2):2047981614560076
pubmed: 25793109
Phys Med Biol. 2015 Jul 21;60(14):5543-56
pubmed: 26134119
J Nucl Med. 2016 Jan;57(1):78-84
pubmed: 26471697
Medicine (Baltimore). 2015 Dec;94(51):e2319
pubmed: 26705220
Cancer Imaging. 2016 Aug 26;16(1):26
pubmed: 27565136
Eur J Nucl Med Mol Imaging. 2016 Dec;43(13):2283-2289
pubmed: 27565153
Childs Nerv Syst. 2016 Oct;32(10):1823-32
pubmed: 27659825
J Nucl Med. 2017 Mar;58(3):399-405
pubmed: 27688481
Radiology. 2016 Nov;281(2):647-649
pubmed: 27755931
Clin Nucl Med. 2017 Mar;42(3):e142-e148
pubmed: 28072621
Nucl Med Commun. 2017 Apr;38(4):325-332
pubmed: 28230714
J Nucl Med. 2017 Oct;58(10):1699-1705
pubmed: 28360205
Semin Nucl Med. 2017 May;47(3):229-241
pubmed: 28417853
Semin Nucl Med. 2017 May;47(3):242-257
pubmed: 28417854
Semin Nucl Med. 2017 May;47(3):258-274
pubmed: 28417855
Br J Radiol. 2017 Aug;90(1077):20170347
pubmed: 28707543

Auteurs

Pietro Zucchetta (P)

1 Nuclear Medicine Unit, Department of Medicine DIMED, University-Hospital of Padova , Padova , Italy.

Marco Branchini (M)

2 Medical Physics Department, Veneto Institute of Oncology IOV-IRCCS , Padova , Italy.

Alessandra Zorz (A)

2 Medical Physics Department, Veneto Institute of Oncology IOV-IRCCS , Padova , Italy.

Valentina Bodanza (V)

1 Nuclear Medicine Unit, Department of Medicine DIMED, University-Hospital of Padova , Padova , Italy.

Diego Cecchin (D)

1 Nuclear Medicine Unit, Department of Medicine DIMED, University-Hospital of Padova , Padova , Italy.

Marta Paiusco (M)

2 Medical Physics Department, Veneto Institute of Oncology IOV-IRCCS , Padova , Italy.

Franco Bui (F)

1 Nuclear Medicine Unit, Department of Medicine DIMED, University-Hospital of Padova , Padova , Italy.

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Classifications MeSH