Cigarette smoking and culture conversion in patients with susceptible and M/XDR-TB.
Adult
Antitubercular Agents
/ pharmacology
Cigarette Smoking
/ adverse effects
Extensively Drug-Resistant Tuberculosis
/ drug therapy
Female
Germany
Humans
Logistic Models
Male
Middle Aged
Mycobacterium tuberculosis
/ drug effects
Retrospective Studies
Sputum
/ microbiology
Time Factors
Treatment Outcome
Tuberculosis, Multidrug-Resistant
/ drug therapy
Young Adult
Journal
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
ISSN: 1815-7920
Titre abrégé: Int J Tuberc Lung Dis
Pays: France
ID NLM: 9706389
Informations de publication
Date de publication:
01 01 2019
01 01 2019
Historique:
entrez:
25
1
2019
pubmed:
25
1
2019
medline:
21
12
2019
Statut:
ppublish
Résumé
Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide. Active cigarette smoking may have a significant impact on treatment responses to anti-tuberculosis treatment. To ascertain the effect of smoking on Sputum cultures of smoking and non-smoking patients with pulmonary TB (PTB) treated at a referral centre in Germany were evaluated. Between January 2012 and March 2017, 247 patients with PTB treated at the Medical Clinic of Research Center Borstel, Borstel, Germany, were included in the study. Of 247 patients, 65 (26.3%) were infected with multidrug-resistant strains of Active cigarette smoking and, to a lesser extent, former cigarette smoking, substantially delayed culture conversion in PTB.
Sections du résumé
BACKGROUND
Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide. Active cigarette smoking may have a significant impact on treatment responses to anti-tuberculosis treatment.
OBJECTIVE
To ascertain the effect of smoking on
METHOD
Sputum cultures of smoking and non-smoking patients with pulmonary TB (PTB) treated at a referral centre in Germany were evaluated.
RESULTS
Between January 2012 and March 2017, 247 patients with PTB treated at the Medical Clinic of Research Center Borstel, Borstel, Germany, were included in the study. Of 247 patients, 65 (26.3%) were infected with multidrug-resistant strains of
CONCLUSION
Active cigarette smoking and, to a lesser extent, former cigarette smoking, substantially delayed culture conversion in PTB.
Identifiants
pubmed: 30674380
doi: 10.5588/ijtld.18.0354
doi:
Substances chimiques
Antitubercular Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM