Phenytoin-induced hypothermia.
drug interactions
epilepsy and seizures
unwanted effects / adverse reactions
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
22 Jan 2019
22 Jan 2019
Historique:
entrez:
25
1
2019
pubmed:
25
1
2019
medline:
14
5
2019
Statut:
epublish
Résumé
A 60-year-old man with cerebral palsy and epilepsy was admitted with acute lethargy and deterioration in coordination. He was noted to be hypothermic at 35°C on admission. Routine work-up revealed toxic levels of phenytoin. No cause of hypothermia could be identified but as his phenytoin levels normalised, his body temperature also improved. There are three other reported cases of phenytoin- induced hypothermia in the literature. Could this be a rare cause of hypothermia?
Identifiants
pubmed: 30674493
pii: 12/1/e227443
doi: 10.1136/bcr-2018-227443
pmc: PMC6347948
pii:
doi:
Substances chimiques
Cytochrome P-450 CYP1A2 Inducers
0
Phenytoin
6158TKW0C5
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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