Cyclin G1 and TASCC regulate kidney epithelial cell G
Animals
Autophagy
Cell Compartmentation
Cell Cycle Checkpoints
Cell Dedifferentiation
Cyclin G1
/ metabolism
Disease Models, Animal
Disease Progression
Epithelial Cells
/ metabolism
Fibrosis
Humans
Kidney
/ pathology
Kidney Tubules, Proximal
/ pathology
LLC-PK1 Cells
Male
Mice
Renal Insufficiency, Chronic
/ pathology
Swine
TOR Serine-Threonine Kinases
/ metabolism
Wound Healing
Journal
Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086
Informations de publication
Date de publication:
23 01 2019
23 01 2019
Historique:
received:
19
09
2018
accepted:
20
12
2018
entrez:
25
1
2019
pubmed:
25
1
2019
medline:
23
2
2020
Statut:
ppublish
Résumé
Fibrosis contributes to the progression of chronic kidney disease (CKD). Severe acute kidney injury can lead to CKD through proximal tubular cell (PTC) cycle arrest in the G
Identifiants
pubmed: 30674655
pii: 11/476/eaav4754
doi: 10.1126/scitranslmed.aav4754
pmc: PMC6527117
mid: NIHMS1020744
pii:
doi:
Substances chimiques
Cyclin G1
0
TOR Serine-Threonine Kinases
EC 2.7.11.1
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIDDK NIH HHS
ID : K01 DK099473
Pays : United States
Organisme : NIDDK NIH HHS
ID : R37 DK039773
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK072381
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK121101
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK114809
Pays : United States
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
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