Multifocal Primary Uveal Melanoma: Clinical and Molecular Characteristics.
Choroidal nevus malignant transformation
Germline BAP1 mutation
Iodine-125 plaque brachytherapy
Multifocal uveal melanoma
Journal
Ocular oncology and pathology
ISSN: 2296-4681
Titre abrégé: Ocul Oncol Pathol
Pays: Switzerland
ID NLM: 101656139
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
30
11
2017
revised:
29
01
2018
entrez:
25
1
2019
pubmed:
25
1
2019
medline:
25
1
2019
Statut:
ppublish
Résumé
We report two patients who developed a second distinct choroidal melanoma in the same eye following successful regression of their first choroidal melanoma after iodine-125 plaque brachytherapy. Neither patient demonstrated ocular melanocytosis, local tumor recurrence, or vitreous seeding. One patient had the second tumor arising from a previously documented choroidal nevus, and after undergoing enucleation, there was no detectable connection between the tumors on histopathologic examination. Germline
Identifiants
pubmed: 30675471
doi: 10.1159/000487891
pii: oop-0005-0008
pmc: PMC6341333
doi:
Types de publication
Journal Article
Langues
eng
Pagination
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