Antibacterial investigation of titanium-copper alloys using luminescent Staphylococcus epidermidis in a direct contact test.


Journal

Materials science & engineering. C, Materials for biological applications
ISSN: 1873-0191
Titre abrégé: Mater Sci Eng C Mater Biol Appl
Pays: Netherlands
ID NLM: 101484109

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 25 10 2017
revised: 18 10 2018
accepted: 16 12 2018
entrez: 26 1 2019
pubmed: 27 1 2019
medline: 6 5 2019
Statut: ppublish

Résumé

Commercially pure titanium (CP-Ti), used as oral implants, is often populated by various bacterial colonies in the oral cavity. These bacteria can cause Peri-implantitis, leading to loss of bone tissue and failure of implants. With the increased awareness of antibiotic resistance, research has been directed towards alternative solutions and recent findings have indicated titanium‑copper (Ti-Cu) alloys as a promising antibacterial material. The aim of this study was to produce homogeneous Ti-Cu alloys, with various concentrations of copper, and to characterise their antibacterial properties through direct contact tests, using luminescent bacteria, in addition to traditional materials characterisation techniques. Samples of CP-Ti and four different Ti-Cu alloys (1, 2.5, 3 and 10 wt%Cu) were produced in an arc-furnace, heated treated and rapidly quenched. X-ray diffraction revealed that Ti

Identifiants

pubmed: 30678959
pii: S0928-4931(17)34236-4
doi: 10.1016/j.msec.2018.12.050
pii:
doi:

Substances chimiques

Alloys 0
Anti-Bacterial Agents 0
Copper 789U1901C5
Titanium D1JT611TNE

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

707-714

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Lee Fowler (L)

Division of Applied Materials Science, Department of Engineering Sciences, The Ångström Laboratory, Uppsala University, Box 534, 751 21 Uppsala, Sweden.

Oscar Janson (O)

Division of Applied Materials Science, Department of Engineering Sciences, The Ångström Laboratory, Uppsala University, Box 534, 751 21 Uppsala, Sweden.

Håkan Engqvist (H)

Division of Applied Materials Science, Department of Engineering Sciences, The Ångström Laboratory, Uppsala University, Box 534, 751 21 Uppsala, Sweden.

Susanne Norgren (S)

Division of Applied Materials Science, Department of Engineering Sciences, The Ångström Laboratory, Uppsala University, Box 534, 751 21 Uppsala, Sweden.

Caroline Öhman-Mägi (C)

Division of Applied Materials Science, Department of Engineering Sciences, The Ångström Laboratory, Uppsala University, Box 534, 751 21 Uppsala, Sweden. Electronic address: caroline.ohman@angstrom.uu.se.

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Classifications MeSH