Technetium-99m-labeled lapachol as an imaging probe for breast tumor identification.

Lapachol marcado con tecnecio 99m como sonda de imágenes para la identificación de tumores de mama.

Journal

Revista espanola de medicina nuclear e imagen molecular
ISSN: 2253-8089
Titre abrégé: Rev Esp Med Nucl Imagen Mol (Engl Ed)
Pays: Spain
ID NLM: 101770941

Informations de publication

Date de publication:
Historique:
received: 31 07 2018
revised: 17 10 2018
accepted: 19 10 2018
pubmed: 27 1 2019
medline: 24 1 2020
entrez: 26 1 2019
Statut: ppublish

Résumé

Breast cancer is a health problem worldwide with high incidence and mortality rates. It is well known that the development of more sensitive and specific diagnostic methods is of great importance since an early diagnosis is essential to successfully treat tumors. Lapachol is a natural compound, belonging to the naphthoquinone group that has been widely used in traditional medicine to treat various illnesses, including cancer. The aim of this study was to evaluate technetium-99m ( To achieve this purpose, lapachol was labeled with Lapachol was successfully labeled with These findings suggest that

Identifiants

pubmed: 30679039
pii: S2253-654X(18)30174-4
doi: 10.1016/j.remn.2018.10.006
pii:
doi:

Substances chimiques

Naphthoquinones 0
Technetium 7440-26-8
lapachol B221938VB6

Types de publication

Journal Article

Langues

eng spa

Sous-ensembles de citation

IM

Pagination

167-172

Informations de copyright

Copyright © 2019 Sociedad Española de Medicina Nuclear e Imagen Molecular. Publicado por Elsevier España, S.L.U. All rights reserved.

Auteurs

S E Miranda (SE)

Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.

J A Lemos (JA)

Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.

R S Fernandes (RS)

Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.

F M Ottoni (FM)

Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.

R J Alves (RJ)

Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.

A Ferretti (A)

Department of Nuclear Medicine, Radiology, NeuroRadiology, Medical Physics, Clinical Laboratory, Microbiology, Pathology, Santa Maria della Misericordia Hospital, Rovigo, Italia.

D Rubello (D)

Department of Nuclear Medicine, Radiology, NeuroRadiology, Medical Physics, Clinical Laboratory, Microbiology, Pathology, Santa Maria della Misericordia Hospital, Rovigo, Italia. Electronic address: domenico.rubello@libero.it.

V N Cardoso (VN)

Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.

A L Branco de Barros (AL)

Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil. Electronic address: brancodebarros@yahoo.com.br.

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Classifications MeSH