Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between


Journal

Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435

Informations de publication

Date de publication:
06 2019
Historique:
received: 18 07 2018
accepted: 21 01 2019
pubmed: 27 1 2019
medline: 19 5 2020
entrez: 26 1 2019
Statut: ppublish

Résumé

The t(4;11)(q21;q23) translocation is associated with high-risk infant pro-B-cell acute lymphoblastic leukemia and arises prenatally during embryonic/fetal hematopoiesis. The developmental/pathogenic contribution of the t(4;11)-resulting

Identifiants

pubmed: 30679325
pii: haematol.2018.202044
doi: 10.3324/haematol.2018.202044
pmc: PMC6545840
doi:

Substances chimiques

Histones 0
MLL-AF4 fusion protein, human 0
Oncogene Proteins, Fusion 0
Myeloid-Lymphoid Leukemia Protein 149025-06-9

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1189-1201

Subventions

Organisme : Medical Research Council
ID : MC_PC_12009
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M008975/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S036113/1
Pays : United Kingdom

Informations de copyright

Copyright© 2019 Ferrata Storti Foundation.

Références

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Auteurs

Clara Bueno (C)

Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Spain cbueno@carrerasresearch.org pmenendez@carrerasresearch.org.
Centro de Investigación Biomédica en Red de Cáncer (CIBER-ONC), ISCIII, Barcelona, Spain.

Fernando J Calero-Nieto (FJ)

Department of Hematology, Cambridge Institute for Medical Research and Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, UK.

Xiaonan Wang (X)

Department of Hematology, Cambridge Institute for Medical Research and Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, UK.

Rafael Valdés-Mas (R)

Dreamgenics S.L. Oviedo. Spain.

Francisco Gutiérrez-Agüera (F)

Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Spain.

Heleia Roca-Ho (H)

Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Spain.

Veronica Ayllon (V)

GENyO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government and University of Granada, Department of Biochemistry and Molecular Biology, Granada, Spain.

Pedro J Real (PJ)

GENyO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government and University of Granada, Department of Biochemistry and Molecular Biology, Granada, Spain.

David Arambilet (D)

Programa de Cáncer, Instituto Hospital del Mar de Investigaciones Médicas. Barcelona. Spain.

Lluis Espinosa (L)

Programa de Cáncer, Instituto Hospital del Mar de Investigaciones Médicas. Barcelona. Spain.
Centro de Investigación Biomédica en Red de Cáncer (CIBER-ONC), ISCIII, Barcelona, Spain.

Raul Torres-Ruiz (R)

Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Spain.

Antonio Agraz-Doblas (A)

Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Spain.
Instituto de Biomedicina y Biotecnología de Cantabria (CSIC-UC-Sodercan), Departamento de Biología Molecular, Universidad de Cantabria, Santander, Spain.

Ignacio Varela (I)

Instituto de Biomedicina y Biotecnología de Cantabria (CSIC-UC-Sodercan), Departamento de Biología Molecular, Universidad de Cantabria, Santander, Spain.

Jasper de Boer (J)

Cancer Section, UCL Great Ormond Street Institute of Child Health, London, UK.

Anna Bigas (A)

Programa de Cáncer, Instituto Hospital del Mar de Investigaciones Médicas. Barcelona. Spain.
Centro de Investigación Biomédica en Red de Cáncer (CIBER-ONC), ISCIII, Barcelona, Spain.

Bertie Gottgens (B)

Department of Hematology, Cambridge Institute for Medical Research and Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, UK.

Rolf Marschalek (R)

Institute of Pharmaceutical Biology, Goethe-University, Frankfurt, Germany.

Pablo Menendez (P)

Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Spain cbueno@carrerasresearch.org pmenendez@carrerasresearch.org.
Centro de Investigación Biomédica en Red de Cáncer (CIBER-ONC), ISCIII, Barcelona, Spain.
Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

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