Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between
Animals
Apoptosis
/ genetics
Cell Cycle
/ genetics
Cell Differentiation
/ genetics
Coculture Techniques
Embryonic Development
/ genetics
Endothelial Cells
/ cytology
Hematopoiesis
/ genetics
Hematopoietic Stem Cells
/ cytology
Histones
/ metabolism
Human Embryonic Stem Cells
/ cytology
Humans
Methylation
Mice
Mice, Knockout
Myeloid-Lymphoid Leukemia Protein
/ genetics
Oncogene Proteins, Fusion
/ genetics
Journal
Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
18
07
2018
accepted:
21
01
2019
pubmed:
27
1
2019
medline:
19
5
2020
entrez:
26
1
2019
Statut:
ppublish
Résumé
The t(4;11)(q21;q23) translocation is associated with high-risk infant pro-B-cell acute lymphoblastic leukemia and arises prenatally during embryonic/fetal hematopoiesis. The developmental/pathogenic contribution of the t(4;11)-resulting
Identifiants
pubmed: 30679325
pii: haematol.2018.202044
doi: 10.3324/haematol.2018.202044
pmc: PMC6545840
doi:
Substances chimiques
Histones
0
MLL-AF4 fusion protein, human
0
Oncogene Proteins, Fusion
0
Myeloid-Lymphoid Leukemia Protein
149025-06-9
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1189-1201Subventions
Organisme : Medical Research Council
ID : MC_PC_12009
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M008975/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S036113/1
Pays : United Kingdom
Informations de copyright
Copyright© 2019 Ferrata Storti Foundation.
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