FDG atrial uptake is associated with an increased prevalence of stroke in patients with atrial fibrillation.
Aged
Atrial Fibrillation
/ complications
Case-Control Studies
Female
Fluorodeoxyglucose F18
/ pharmacokinetics
Glucose
/ metabolism
Heart
/ diagnostic imaging
Heart Atria
/ diagnostic imaging
Humans
Image Processing, Computer-Assisted
Inflammation
Male
Middle Aged
Myocardium
/ pathology
Positron Emission Tomography Computed Tomography
Prevalence
Retrospective Studies
Stroke
/ complications
Atrial fibrillation
FDG
Inflammation
Positron emission tomography (PET)
Stroke
Journal
European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
13
10
2018
accepted:
15
01
2019
pubmed:
27
1
2019
medline:
21
7
2020
entrez:
26
1
2019
Statut:
ppublish
Résumé
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with an increased risk of stroke. Indeed, silent AF is frequently identified in unexplained ischemic stroke. We retrospectively enrolled 128 patients (64 consecutive patients with AF and 64 without AF as the control group, matched for age and sex) who underwent Diffuse right atrial uptake was present in a third of patients with AF and only two patients in the control group. FDG uptake intensity of both atria was significantly associated with the underlying heart rhythm. The occurrence of stroke was strongly associated with detectable atrial uptake in multivariate analysis, with an odds ratio superior to that of other known risk factors. This study shows a significant correlation between FDG atrial uptake and AF. While inconsistent, this pattern seems to be associated with an increased prevalence of cardioembolic stroke.
Identifiants
pubmed: 30680588
doi: 10.1007/s00259-019-4274-6
pii: 10.1007/s00259-019-4274-6
doi:
Substances chimiques
Fluorodeoxyglucose F18
0Z5B2CJX4D
Glucose
IY9XDZ35W2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1268-1275Références
Ann Nucl Med. 1999 Feb;13(1):55-9
pubmed: 10202949
J Mol Cell Cardiol. 2001 Dec;33(12):2083-94
pubmed: 11735256
Cardiovasc Res. 2002 May;54(2):230-46
pubmed: 12062329
J Biol Chem. 1992 Jun 15;267(17):11665-8
pubmed: 1376309
Am Heart J. 2004 Sep;148(3):462-6
pubmed: 15389233
Clin Nucl Med. 2005 Mar;30(3):177-9
pubmed: 15722821
Circ Res. 2005 May 13;96(9):1022-9
pubmed: 15817885
Cardiovasc Res. 2005 Sep 1;67(4):655-66
pubmed: 15913581
Circulation. 2006 Aug 15;114(7):e257-354
pubmed: 16908781
J Nucl Med. 2007 Jun;48(6):932-45
pubmed: 17504879
Int J Cardiol. 2010 Jun 25;142(1):22-8
pubmed: 19178964
Heart Rhythm. 2009 Apr;6(4):454-60
pubmed: 19324302
Europace. 2012 Oct;14(10):1385-413
pubmed: 22923145
Eur Heart J. 2015 Apr 1;36(13):795-805a
pubmed: 23525094
Neurology. 2013 Apr 23;80(17):1546-50
pubmed: 23535493
Clin Nucl Med. 2014 Feb;39(2):167-9
pubmed: 24217538
Am J Cardiol. 2014 May 1;113(9):1505-8
pubmed: 24656480
Q J Nucl Med Mol Imaging. 2014 Dec;58(4):424-39
pubmed: 24732679
Am J Med. 2015 May;128(5):509-18.e2
pubmed: 25534423
J Am Heart Assoc. 2015 Jan 21;4(1):e001486
pubmed: 25609415
Int J Cardiovasc Imaging. 2016 Jan;32(1):113-9
pubmed: 26411879
Medicine (Baltimore). 2016 Mar;95(9):e3002
pubmed: 26945422
Radiol Case Rep. 2015 Nov 06;3(1):120
pubmed: 27303503
J Biomark. 2016;2016:8160393
pubmed: 27446629
Eur J Cardiothorac Surg. 2016 Nov;50(5):e1-e88
pubmed: 27663299
Circ Cardiovasc Imaging. 2016 Oct;9(10):
pubmed: 27729358
Int J Cardiovasc Imaging. 2017 Aug;33(8):1271-1276
pubmed: 28229312
Circ Cardiovasc Imaging. 2017 Mar;10(3):e005585
pubmed: 28298285
Circ J. 2017 Nov 24;81(12):1749-1757
pubmed: 29070758
BMC Med Imaging. 2018 May 9;18(1):11
pubmed: 29743027
J Nucl Cardiol. 2018 Aug 7;:null
pubmed: 30088193
FEBS Lett. 1993 Nov 29;335(1):37-40
pubmed: 8243661
Physiol Res. 1993;42(1):1-6
pubmed: 8329368
Circulation. 1997 Aug 19;96(4):1180-4
pubmed: 9286947