Thermostable cellulases: Current status and perspectives.


Journal

Bioresource technology
ISSN: 1873-2976
Titre abrégé: Bioresour Technol
Pays: England
ID NLM: 9889523

Informations de publication

Date de publication:
May 2019
Historique:
received: 29 11 2018
revised: 09 01 2019
accepted: 11 01 2019
pubmed: 28 1 2019
medline: 7 9 2019
entrez: 28 1 2019
Statut: ppublish

Résumé

It is envisaged that the utilization of lignocellulosic biomass for ethanol production for transport sector, would make cellulases the most demanded industrial enzyme. The greatest potential of cellulolytic enzymes lies in ethanol production from biomass by enzymatic hydrolysis of cellulose but low thermostability and low titer of cellulase production resulting into high cost of the enzyme which is the major set-back. A number of research groups are working on cellulase to improve its thermostability so as to be able to perform hydrolysis at elevated temperatures which would eventually increase the efficiency of cellulose hydrolysis. The technologies developed from lignocellulosic biomass via cellulose hydrolysis promise environmental and economical sustainability in the long run along with non-dependence on nonrenewable energy source. This review deals with the important sources of thermostable cellulases, mechanism, its regulation, strategies to enhance the thermostability further with respect to its importance for biofuel applications.

Identifiants

pubmed: 30685132
pii: S0960-8524(19)30062-8
doi: 10.1016/j.biortech.2019.01.049
pii:
doi:

Substances chimiques

Biofuels 0
Cellulose 9004-34-6
Lignin 9005-53-2
Cellulases EC 3.2.1.-

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

385-392

Informations de copyright

Copyright © 2019. Published by Elsevier Ltd.

Auteurs

Anil K Patel (AK)

Department of Chemical and Biological Engineering, Korea University, Seoul 02841, Republic of Korea.

Reeta Rani Singhania (RR)

Centre for Energy and Environmental Sustainability, Lucknow 226 029, India. Electronic address: reetasinghania@gmail.com.

Sang Jun Sim (SJ)

Department of Chemical and Biological Engineering, Korea University, Seoul 02841, Republic of Korea.

Ashok Pandey (A)

Centre for Innovation and Translational Research, Indian Institute of Toxicological Research, Lucknow 226 001, India.

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Classifications MeSH