Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel K
Acquired long QT syndrome (aLQTS)
Cardiac electrophysiology
Kv11.1
Rapid delayed rectifier current (IKr,)
Safety pharmacology
Sudden cardiac death (SCD)
Journal
Research in veterinary science
ISSN: 1532-2661
Titre abrégé: Res Vet Sci
Pays: England
ID NLM: 0401300
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
27
10
2018
revised:
19
12
2018
accepted:
08
01
2019
pubmed:
28
1
2019
medline:
16
5
2019
entrez:
28
1
2019
Statut:
ppublish
Résumé
The voltage-gated K To screen a series of commonly used drugs in equine medicine for interaction with K High-throughput screening of selected compounds on human K Acepromazine maleat (IC The results suggest that drug interaction with K
Sections du résumé
BACKGROUND
BACKGROUND
The voltage-gated K
AIM
OBJECTIVE
To screen a series of commonly used drugs in equine medicine for interaction with K
METHODS
METHODS
High-throughput screening of selected compounds on human K
RESULTS
RESULTS
Acepromazine maleat (IC
CONCLUSION
CONCLUSIONS
The results suggest that drug interaction with K
Identifiants
pubmed: 30685649
pii: S0034-5288(18)34210-3
doi: 10.1016/j.rvsc.2019.01.009
pii:
doi:
Substances chimiques
ERG1 Potassium Channel
0
Pharmaceutical Preparations
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
239-246Informations de copyright
Copyright © 2019. Published by Elsevier Ltd.