Ultrapure Filter does not Confer Short-Term Benefits over Two Reverse Osmosis Systems in Chronic Hemodialysis Patients.
Aged
Blood Pressure
/ physiology
C-Reactive Protein
/ analysis
Dialysis Solutions
/ chemistry
Female
Humans
Kidney Failure, Chronic
/ therapy
Male
Middle Aged
Osmosis
Renal Dialysis
/ instrumentation
Retrospective Studies
Serum Albumin
/ analysis
Ultrafiltration
/ instrumentation
Water Purification
/ instrumentation
Journal
The Israel Medical Association journal : IMAJ
ISSN: 1565-1088
Titre abrégé: Isr Med Assoc J
Pays: Israel
ID NLM: 100930740
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
entrez:
28
1
2019
pubmed:
28
1
2019
medline:
28
5
2019
Statut:
ppublish
Résumé
Dialysate purity contributes to the inflammatory response that afflicts hemodialysis patients. To compare the clinical and laboratory effects of using ultrapure water produced by a water treatment system including two reverse osmosis (RO) units in series, with a system that also includes an ultrapure filter (UPF). We performed a retrospective study in 193 hemodialysis patients during two periods: period A (no UPF, 6 months) and period B (same patients, with addition of UPF, 18 months), and a historical cohort of patients treated in the same dialysis unit 2 years earlier, which served as a control group. Mean C-reactive protein, serum albumin and systolic blood pressure worsened in period B compared to period A and in the controls. A double RO system to produce ultrapure water is not inferior to the use of ultrapure filters.
Sections du résumé
BACKGROUND
BACKGROUND
Dialysate purity contributes to the inflammatory response that afflicts hemodialysis patients.
OBJECTIVES
OBJECTIVE
To compare the clinical and laboratory effects of using ultrapure water produced by a water treatment system including two reverse osmosis (RO) units in series, with a system that also includes an ultrapure filter (UPF).
METHODS
METHODS
We performed a retrospective study in 193 hemodialysis patients during two periods: period A (no UPF, 6 months) and period B (same patients, with addition of UPF, 18 months), and a historical cohort of patients treated in the same dialysis unit 2 years earlier, which served as a control group.
RESULTS
RESULTS
Mean C-reactive protein, serum albumin and systolic blood pressure worsened in period B compared to period A and in the controls.
CONCLUSIONS
CONCLUSIONS
A double RO system to produce ultrapure water is not inferior to the use of ultrapure filters.
Substances chimiques
Dialysis Solutions
0
Serum Albumin
0
C-Reactive Protein
9007-41-4
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM