Determinants of stem cell lineage differentiation toward chondrogenesis versus adipogenesis.
Adipogenesis
/ physiology
Adipose Tissue
/ cytology
Adolescent
Adult
Adult Stem Cells
/ cytology
Aged
Aged, 80 and over
Animals
Cartilage, Articular
/ cytology
Cell Lineage
Cellular Senescence
/ physiology
Chondrogenesis
/ physiology
Humans
Mesenchymal Stem Cells
/ cytology
Mice
Middle Aged
Rats
Signal Transduction
/ physiology
Young Adult
Adipogenesis,
Chondrogenesis
Lineage differentiation
Stem cell
Journal
Cellular and molecular life sciences : CMLS
ISSN: 1420-9071
Titre abrégé: Cell Mol Life Sci
Pays: Switzerland
ID NLM: 9705402
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
received:
20
07
2018
accepted:
15
01
2019
revised:
10
12
2018
pubmed:
29
1
2019
medline:
2
5
2019
entrez:
29
1
2019
Statut:
ppublish
Résumé
Adult stem cells, also termed as somatic stem cells, are undifferentiated cells, detected among differentiated cells in a tissue or an organ. Adult stem cells can differentiate toward lineage specific cell types of the tissue or organ in which they reside. They also have the ability to differentiate into mature cells of mesenchymal tissues, such as cartilage, fat and bone. Despite the fact that the balance has been comprehensively scrutinized between adipogenesis and osteogenesis and between chondrogenesis and osteogenesis, few reviews discuss the relationship between chondrogenesis and adipogenesis. In this review, the developmental and transcriptional crosstalk of chondrogenic and adipogenic lineages are briefly explored, followed by elucidation of signaling pathways and external factors guiding lineage determination between chondrogenic and adipogenic differentiation. An in-depth understanding of overlap and discrepancy between these two mesenchymal tissues in lineage differentiation would benefit regeneration of high-quality cartilage tissues and adipose tissues for clinical applications.
Identifiants
pubmed: 30689010
doi: 10.1007/s00018-019-03017-4
pii: 10.1007/s00018-019-03017-4
pmc: PMC6456412
mid: NIHMS1519753
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1653-1680Subventions
Organisme : NIAMS NIH HHS
ID : R01 AR067747
Pays : United States
Organisme : National Institute of Arthritis and Musculoskeletal and Skin Diseases
ID : 1R01AR067747-01A1
Organisme : Musculoskeletal Transplant Foundation
ID : Established Investigator Award
Références
Science. 1999 Apr 2;284(5411):143-7
pubmed: 10102814
J Cell Physiol. 1999 Oct;181(1):67-73
pubmed: 10457354
Genes Dev. 1999 Aug 15;13(16):2072-86
pubmed: 10465785
Clin Orthop Relat Res. 2000 Jan;(370):295-310
pubmed: 10660725
Dev Dyn. 2000 Apr;217(4):401-14
pubmed: 10767084
J Cell Biol. 2000 May 1;149(3):667-82
pubmed: 10791980
Mol Endocrinol. 2000 Jun;14(6):805-13
pubmed: 10847583
J Rehabil Res Dev. 2000 Mar-Apr;37(2):127-33
pubmed: 10850818
DNA Cell Biol. 2000 May;19(5):275-81
pubmed: 10855794
FEBS Lett. 2000 Jun 23;475(3):201-4
pubmed: 10869556
Biochem Biophys Res Commun. 2000 Jul 5;273(2):609-13
pubmed: 10873653
Science. 2000 Aug 11;289(5481):950-3
pubmed: 10937998
J Bone Miner Res. 2000 Sep;15(9):1659-68
pubmed: 10976986
Physiol Genomics. 2000 Aug 09;3(2):75-82
pubmed: 11015602
Mol Cell Biol. 2001 Apr;21(7):2521-32
pubmed: 11259600
Exp Cell Res. 2001 Aug 15;268(2):189-200
pubmed: 11478845
J Cell Sci. 2001 Jun;114(Pt 11):2085-94
pubmed: 11493644
Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12532-7
pubmed: 11606718
Biochem Biophys Res Commun. 2002 Jan 18;290(2):763-9
pubmed: 11785965
Dev Cell. 2002 Mar;2(3):331-41
pubmed: 11879638
J Biol Chem. 2002 Aug 23;277(34):30998-1004
pubmed: 12055200
J Biol Chem. 2002 Aug 30;277(35):31526-33
pubmed: 12072435
J Biol Chem. 2002 Aug 23;277(34):30870-8
pubmed: 12077113
Nature. 2002 Jul 4;418(6893):41-9
pubmed: 12077603
Ann N Y Acad Sci. 2002 Jun;961:172-7
pubmed: 12081893
Am J Respir Cell Mol Biol. 2002 Jul;27(1):8-16
pubmed: 12091240
J Biol Chem. 2002 Nov 29;277(48):46226-32
pubmed: 12270934
Cell Calcium. 2002 Oct;32(4):165-74
pubmed: 12379176
J Biol Chem. 2003 Mar 14;278(11):9609-19
pubmed: 12524424
J Cell Sci. 2003 May 15;116(Pt 10):2015-28
pubmed: 12679385
J Biol Chem. 2003 Sep 19;278(38):36563-71
pubmed: 12853454
Biochem J. 2003 Dec 15;376(Pt 3):607-13
pubmed: 12954078
J Orthop Res. 2003 Nov;21(6):1090-7
pubmed: 14554223
Tissue Eng. 2003 Dec;9(6):1301-12
pubmed: 14670117
Bone. 2003 Dec;33(6):919-26
pubmed: 14678851
Differentiation. 2003 Dec;71(9-10):567-77
pubmed: 14686954
Osteoarthritis Cartilage. 2004 Jan;12(1):25-37
pubmed: 14697680
J Cell Sci. 2004 Jan 26;117(Pt 3):417-25
pubmed: 14702386
Cell. 2004 Mar 5;116(5):639-48
pubmed: 15006347
J Bone Miner Res. 2004 Mar;19(3):463-70
pubmed: 15040835
Mol Cell Biol. 2004 Apr;24(8):3505-13
pubmed: 15060169
Dev Cell. 2004 Apr;6(4):483-95
pubmed: 15068789
J Biol Chem. 2004 Oct 22;279(43):45020-7
pubmed: 15308623
J Cell Physiol. 2005 May;203(2):398-409
pubmed: 15521064
FEBS Lett. 2004 Nov 5;577(1-2):277-83
pubmed: 15527799
Arthritis Rheum. 2004 Nov;50(11):3561-73
pubmed: 15529345
Exp Cell Res. 2004 Dec 10;301(2):280-92
pubmed: 15530863
Diabetes. 2004 Dec;53(12):3097-106
pubmed: 15561939
Aging Cell. 2004 Dec;3(6):379-89
pubmed: 15569355
J Endocrinol. 2004 Dec;183(3):477-86
pubmed: 15590974
Cell Tissue Res. 2005 May;320(2):269-76
pubmed: 15778851
J Biomater Sci Polym Ed. 2005;16(1):57-77
pubmed: 15796305
Biochem J. 2005 Aug 1;389(Pt 3):723-9
pubmed: 15801908
J Cell Physiol. 2005 Nov;205(2):194-201
pubmed: 15880640
Biochem Biophys Res Commun. 2005 Aug 12;333(4):1178-84
pubmed: 15975549
Int J Biochem Cell Biol. 2006 Feb;38(2):183-95
pubmed: 16183324
Cell Metab. 2006 Jan;3(1):25-34
pubmed: 16399502
Arthritis Rheum. 2006 Feb;54(2):433-42
pubmed: 16447218
Stem Cells. 2006 Jun;24(6):1487-95
pubmed: 16469821
BMC Cell Biol. 2006 Mar 10;7:14
pubmed: 16529651
J Biol Chem. 2006 May 12;281(19):13134-40
pubmed: 16565087
Anat Histol Embryol. 2006 Aug;35(4):271-8
pubmed: 16836593
Biorheology. 2006;43(3,4):455-70
pubmed: 16912417
Cell. 2006 Aug 25;126(4):677-89
pubmed: 16923388
Lipids Health Dis. 2006 Oct 18;5:27
pubmed: 17049073
Stem Cells. 2007 Mar;25(3):655-63
pubmed: 17124008
Nat Rev Mol Cell Biol. 2006 Dec;7(12):885-96
pubmed: 17139329
J Cell Biochem. 2007 May 1;101(1):80-8
pubmed: 17212358
J Cell Biochem. 2007 Oct 15;102(3):626-37
pubmed: 17497692
Osteoarthritis Cartilage. 2007 Oct;15(10):1178-89
pubmed: 17502159
Development. 2007 Jun;134(12):2283-92
pubmed: 17507398
Arthritis Rheum. 2007 Jun;56(6):1869-79
pubmed: 17530715
Arthritis Res Ther. 2007;9(3):R55
pubmed: 17537234
Biochem Biophys Res Commun. 2007 Jul 27;359(2):239-44
pubmed: 17543283
Cell Metab. 2007 Jul;6(1):38-54
pubmed: 17618855
Circ Res. 2007 Sep 14;101(6):581-9
pubmed: 17673669
Bone. 2007 Oct;41(4):575-83
pubmed: 17690025
Biochem Biophys Res Commun. 2007 Nov 16;363(2):276-82
pubmed: 17888405
Aging Cell. 2007 Dec;6(6):745-57
pubmed: 17925003
Cell. 2007 Oct 19;131(2):242-56
pubmed: 17956727
J Orthop Sci. 2007 Nov;12(6):555-61
pubmed: 18040638
Stem Cells. 2008 Apr;26(4):1037-46
pubmed: 18258719
Biochem Biophys Res Commun. 2008 Apr 18;368(4):990-5
pubmed: 18267113
J Orthop Res. 2008 Jul;26(7):910-7
pubmed: 18302252
J Cell Physiol. 2008 Sep;216(3):708-15
pubmed: 18366089
FEBS Lett. 2008 Sep 22;582(21-22):3201-5
pubmed: 18708054
Nature. 2008 Aug 21;454(7207):961-7
pubmed: 18719582
Nature. 2008 Aug 21;454(7207):1000-4
pubmed: 18719589
Arthritis Rheum. 2008 Sep;58(9):2754-63
pubmed: 18759300
Cell Prolif. 2008 Dec;41(6):859-874
pubmed: 19040566
J Cell Sci. 2009 Feb 15;122(Pt 4):546-53
pubmed: 19174467
Cell Metab. 2009 Mar;9(3):287-302
pubmed: 19254573
Osteoarthritis Cartilage. 2009 Aug;17(8):1065-75
pubmed: 19254740
FEBS J. 2009 Apr;276(8):2348-58
pubmed: 19348006
J Cell Mol Med. 2010 Jun;14(6A):1338-46
pubmed: 19432813
Exp Hematol. 2009 Jul;37(7):867-875.e1
pubmed: 19540436
Cytotherapy. 2009;11(5):584-94
pubmed: 19626496
Tissue Eng Part A. 2010 Jul;16(7):2405-13
pubmed: 19737074
Tissue Eng Part A. 2010 Mar;16(3):1009-19
pubmed: 19842915
Cytokine Growth Factor Rev. 2009 Oct-Dec;20(5-6):523-31
pubmed: 19896888
Am J Physiol Cell Physiol. 2010 Feb;298(2):C355-64
pubmed: 19940068
J Cell Biochem. 2010 Feb 1;109(2):406-16
pubmed: 19950204
J Cell Physiol. 2010 Apr;223(1):84-93
pubmed: 20049852
J Tissue Eng Regen Med. 2010 Jul;4(5):374-86
pubmed: 20058244
J Orthop Res. 2010 Jun;28(6):834-40
pubmed: 20058274
Tissue Eng Part A. 2010 Jun;16(6):1845-55
pubmed: 20067399
Cell. 2010 Jan 8;140(1):148-60
pubmed: 20074523
Stem Cells. 2010 Mar 31;28(3):564-72
pubmed: 20082286
J Biosci Bioeng. 2010 Mar;109(3):297-303
pubmed: 20159581
Tissue Eng Part A. 2010 Aug;16(8):2605-16
pubmed: 20367246
Cell Tissue Res. 2010 Jul;341(1):111-20
pubmed: 20496083
Cell Prolif. 2010 Jun;43(3):249-61
pubmed: 20546243
Cell Prolif. 2010 Aug;43(4):333-43
pubmed: 20590658
Biochem Biophys Res Commun. 2010 Sep 3;399(4):721-6
pubmed: 20692234
J Cell Physiol. 2011 Mar;226(3):739-48
pubmed: 20717928
J Biomed Mater Res A. 2010 Sep 1;94(3):978-87
pubmed: 20730935
Hum Gene Ther. 2010 Oct;21(10):1226-38
pubmed: 20804388
Tissue Eng Part A. 2011 Apr;17(7-8):991-1002
pubmed: 21091327
J Mol Endocrinol. 2011 Mar 07;46(2):R65-72
pubmed: 21247979
Biochem Biophys Res Commun. 2011 Apr 1;407(1):68-73
pubmed: 21356196
J Tissue Eng Regen Med. 2012 Mar;6(3):205-13
pubmed: 21360690
Biomaterials. 2011 Jun;32(16):3921-30
pubmed: 21397942
Pharmacol Ther. 2011 Jul;131(1):142-70
pubmed: 21420431
Clin Orthop Relat Res. 2011 Oct;469(10):2744-53
pubmed: 21424832
Cell. 1990 Apr 20;61(2):203-12
pubmed: 2158859
Stem Cells Dev. 2012 Mar 20;21(5):790-800
pubmed: 21627568
Bone. 2012 Feb;50(2):477-89
pubmed: 21872687
Cells Tissues Organs. 2012;195(5):414-27
pubmed: 21893933
Tissue Eng Part A. 2012 Apr;18(7-8):715-24
pubmed: 21988555
Cell Stress Chaperones. 2012 Mar;17(2):181-90
pubmed: 21993906
Eur Cell Mater. 2011 Nov 24;22:302-19; discussion 319-20
pubmed: 22116649
Diabetes. 2012 Jan;61(1):124-36
pubmed: 22187378
Biochem Biophys Res Commun. 2012 Mar 16;419(3):573-7
pubmed: 22374070
Stem Cell Res Ther. 2012 Mar 02;3(2):9
pubmed: 22385573
Mol Endocrinol. 2012 May;26(5):798-808
pubmed: 22422618
Cell Prolif. 2012 Jun;45(3):225-38
pubmed: 22507457
J Mech Behav Biomed Mater. 2012 Jul;11:102-11
pubmed: 22658159
Biomaterials. 2012 Sep;33(26):6042-51
pubmed: 22677190
Biochem Biophys Res Commun. 2012 Jul 13;423(4):672-8
pubmed: 22695113
J Biomed Mater Res A. 2012 Dec;100(12):3344-52
pubmed: 22733694
Tissue Eng Part B Rev. 2012 Dec;18(6):436-44
pubmed: 22741572
Vet J. 2013 Feb;195(2):248-51
pubmed: 22771146
Histochem Cell Biol. 2012 Dec;138(6):833-45
pubmed: 22886144
Cell Metab. 2012 Sep 5;16(3):348-62
pubmed: 22940198
Cell Biol Int. 2012;36(12):1161-70
pubmed: 22974058
Biochem Biophys Res Commun. 2012 Oct 5;426(4):544-50
pubmed: 22982316
Cell Prolif. 2012 Dec;45(6):538-44
pubmed: 23046039
Nat Rev Mol Cell Biol. 2012 Dec;13(12):767-79
pubmed: 23151663
J Tissue Eng Regen Med. 2015 Dec;9(12):E239-51
pubmed: 23193064
Biochem Biophys Res Commun. 2013 Jan 18;430(3):1132-9
pubmed: 23237809
Biochem J. 2013 Feb 15;450(1):9-21
pubmed: 23343194
J Clin Endocrinol Metab. 2013 Mar;98(3):E503-8
pubmed: 23393180
Stem Cells Dev. 2013 Jul 15;22(14):2083-93
pubmed: 23442010
Cytotherapy. 2013 Jul;15(7):805-19
pubmed: 23477785
Biomaterials. 2013 Jun;34(17):4259-65
pubmed: 23489921
Stem Cell Res Ther. 2013 Mar 12;4(2):28
pubmed: 23497794
Biomaterials. 2013 Jul;34(20):4725-38
pubmed: 23562051
J Tissue Eng Regen Med. 2016 Feb;10(2):149-61
pubmed: 23576360
J Cell Sci. 2013 Jul 1;126(Pt 13):2890-902
pubmed: 23606745
J Cell Mol Med. 2013 Aug;17(8):958-65
pubmed: 23802593
Acta Biomater. 2013 Nov;9(11):9012-26
pubmed: 23851171
Biomaterials. 2013 Nov;34(34):8581-8
pubmed: 23953825
Sci Rep. 2013;3:2683
pubmed: 24042188
Stem Cells Int. 2013;2013:232896
pubmed: 24082888
Cell Death Dis. 2013 Oct 03;4:e832
pubmed: 24091675
Biomaterials. 2014 Jan;35(2):642-53
pubmed: 24148243
J Biol Chem. 2014 Jan 31;289(5):2852-63
pubmed: 24344131
J Biomed Mater Res A. 2014 Nov;102(11):3998-4008
pubmed: 24375991
Mol Cell Biochem. 2014 May;390(1-2):123-31
pubmed: 24474615
Biophys J. 2014 Mar 18;106(6):1421-31
pubmed: 24655518
J Clin Endocrinol Metab. 2014 Jul;99(7):E1183-90
pubmed: 24758182
Mater Sci Eng C Mater Biol Appl. 2014 Jul 1;40:316-23
pubmed: 24857499
Cell Tissue Res. 2014 Oct;358(1):149-64
pubmed: 24927918
Stem Cell Res Ther. 2014 Aug 27;5(4):103
pubmed: 25163769
Adv Drug Deliv Rev. 2015 Apr;84:107-22
pubmed: 25174307
Cell Tissue Bank. 2015 Jun;16(2):195-207
pubmed: 25204398
Eur Cell Mater. 2014 Oct 28;28:358-71
pubmed: 25350251
Biomaterials. 2015 Jan;38:72-85
pubmed: 25453975
Osteoarthritis Cartilage. 2015 Mar;23(3):443-53
pubmed: 25464167
Stem Cells Dev. 2015 Apr 15;24(8):995-1007
pubmed: 25519748
Mol Cell Endocrinol. 2015 Mar 5;403:30-8
pubmed: 25596548
Biochem Biophys Res Commun. 2015 Feb 20;457(4):647-52
pubmed: 25603052
Biomed Res. 2015;36(1):21-9
pubmed: 25749148
J Bone Miner Res. 2015 Sep;30(9):1585-96
pubmed: 25753754
Acta Biomater. 2015 Jul;20:39-50
pubmed: 25861949
Stem Cell Res Ther. 2015 Mar 12;6:21
pubmed: 25889814
Tissue Eng Part A. 2015 Sep;21(17-18):2323-33
pubmed: 26035347
Histochem Cell Biol. 2015 Sep;144(3):261-72
pubmed: 26105025
Tissue Eng Part A. 2015 Sep;21(17-18):2460-71
pubmed: 26123891
Cell Physiol Biochem. 2015;36(5):1991-2002
pubmed: 26202359
PLoS One. 2015 Aug 11;10(8):e0135519
pubmed: 26262877
J Cell Physiol. 2016 May;231(5):1033-44
pubmed: 26363135
Exp Cell Res. 2015 Nov 1;338(2):136-48
pubmed: 26384550
Biochem Biophys Res Commun. 2015 Nov 27;467(4):935-40
pubmed: 26471299
ACS Appl Mater Interfaces. 2016 Aug 31;8(34):21903-13
pubmed: 26600563
Acta Biomater. 2016 Jan;30:212-221
pubmed: 26602826
Eur Cell Mater. 2016 Jan 05;31:59-78
pubmed: 26728499
PLoS One. 2016 Feb 01;11(2):e0148173
pubmed: 26828589
Stem Cells Int. 2016;2016:9364974
pubmed: 26839571
Cell Death Differ. 2016 Jul;23(7):1128-39
pubmed: 26868907
J Cell Biochem. 2016 Sep;117(9):2128-37
pubmed: 26888666
Eur Cell Mater. 2016 Feb 22;31:174-90
pubmed: 26898843
Cartilage. 2016 Jan;7(1):92-103
pubmed: 26958321
Stem Cells. 2016 Jul;34(7):1934-46
pubmed: 26990002
J Cell Biochem. 2017 Jan;118(1):172-181
pubmed: 27292615
Tissue Eng Part A. 2016 Aug;22(15-16):1036-46
pubmed: 27411850
Biochem Biophys Res Commun. 2016 Sep 16;478(2):727-32
pubmed: 27498031
Semin Cell Dev Biol. 2017 Feb;62:50-56
pubmed: 27771363
Sci Rep. 2016 Dec 08;6:38616
pubmed: 27929080
Sci Rep. 2016 Dec 22;6:39302
pubmed: 28004813
ACS Appl Mater Interfaces. 2017 Mar 15;9(10):8581-8588
pubmed: 28233976
Cell Tissue Res. 2017 Oct;370(1):53-70
pubmed: 28413859
J Cell Physiol. 2018 Feb;233(2):1156-1167
pubmed: 28460416
Sci Rep. 2017 Aug 25;7(1):9421
pubmed: 28842627
Cell Calcium. 2017 Nov;67:74-80
pubmed: 29029793
Cytotechnology. 2018 Apr;70(2):819-829
pubmed: 29352392
Proc Natl Acad Sci U S A. 1985 Dec;82(24):8530-4
pubmed: 3001708
Stem Cells Int. 2018 Jul 11;2018:6545071
pubmed: 30123291
Cell Physiol Biochem. 2018;51(1):154-172
pubmed: 30439703
Growth Factors. 1993;9(1):57-71
pubmed: 8347351
J Biol Chem. 1993 Apr 5;268(10):7358-64
pubmed: 8385105
Endocrinology. 1993 Apr;132(4):1603-8
pubmed: 8462458
Science. 1996 Aug 2;273(5275):663-6
pubmed: 8662561
Development. 1996 Dec;122(12):3969-79
pubmed: 9012517
J Biol Chem. 1997 Nov 21;272(47):29729-34
pubmed: 9368042
Endocrinology. 1998 Apr;139(4):1638-44
pubmed: 9528944
J Bone Joint Surg Am. 1998 Dec;80(12):1745-57
pubmed: 9875932