A novel intermittent negative air pressure device ameliorates obstructive sleep apnea syndrome in adults.
Apnea–hypopnea index
Intermittent negative air pressure
Intraoral device
Obstructive sleep apnea syndrome
Oral pressure therapy
Sleep-disordered breathing
Journal
Sleep & breathing = Schlaf & Atmung
ISSN: 1522-1709
Titre abrégé: Sleep Breath
Pays: Germany
ID NLM: 9804161
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
04
09
2018
accepted:
27
12
2018
revised:
22
12
2018
pubmed:
29
1
2019
medline:
3
11
2020
entrez:
29
1
2019
Statut:
ppublish
Résumé
Patients with obstructive sleep apnea syndrome (OSAS) have difficulties in compliance with continuous positive airway pressure (CPAP) and the treatment outcome is heterogeneous. We proposed a proof-of-concept study of a novel intermittent negative air pressure (iNAP®) device for physicians to apply on patients who have failed or refused to use CPAP. The iNAP® device retains the tongue and the soft palate in a forward position to decrease airway obstruction. A full nightly usage with the device was evaluated with polysomnography. Subgrouping by baseline apnea-hypopnea index (AHI) and body mass index (BMI) with different treatment response criteria was applied to characterize the responder group of this novel device. Thirty-five patients were enrolled: age 41.9 ± 12.2 years (mean ± standard deviation), BMI 26.6 ± 4.3 kg/m In a proof-of-concept study, the device attained response to treatment as defined, in more than half of the moderate and non-obese OSAS patients, with minimal side effects.
Identifiants
pubmed: 30690676
doi: 10.1007/s11325-018-01778-z
pii: 10.1007/s11325-018-01778-z
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
849-856Références
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