A computational study of lateral phase separation in biological membranes.
lateral phase separation
surface Allen-Chan equation
surface Cahn-Hilliard equation
trace finite element method
Journal
International journal for numerical methods in biomedical engineering
ISSN: 2040-7947
Titre abrégé: Int J Numer Method Biomed Eng
Pays: England
ID NLM: 101530293
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
21
08
2018
revised:
25
11
2018
accepted:
31
12
2018
pubmed:
30
1
2019
medline:
17
1
2020
entrez:
30
1
2019
Statut:
ppublish
Résumé
Conservative and non-conservative phase-field models are considered for the numerical simulation of lateral phase separation and coarsening in biological membranes. An unfitted finite element method is proposed to allow for a flexible treatment of complex shapes in the absence of an explicit surface parametrization. For a set of biologically relevant shapes and parameter values, the paper compares the dynamic coarsening produced by conservative and non-conservative numerical models, its dependence on certain geometric characteristics and convergence to the final equilibrium.
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
e3181Informations de copyright
© 2019 John Wiley & Sons, Ltd.