Monod-Wyman-Changeux Allosteric Shift Analysis in Mutant


Journal

Molecular pharmacology
ISSN: 1521-0111
Titre abrégé: Mol Pharmacol
Pays: United States
ID NLM: 0035623

Informations de publication

Date de publication:
04 2019
Historique:
received: 25 10 2018
accepted: 19 01 2019
pubmed: 31 1 2019
medline: 15 6 2019
entrez: 31 1 2019
Statut: ppublish

Résumé

Propofol, etomidate, and barbiturate anesthetics are allosteric coagonists at pentameric

Identifiants

pubmed: 30696720
pii: mol.118.115048
doi: 10.1124/mol.118.115048
pmc: PMC6399575
doi:

Substances chimiques

Anesthetics 0
Barbiturates 0
Protein Subunits 0
Receptors, GABA-A 0
barbituric acid WQ92Y2793G
Propofol YI7VU623SF
Etomidate Z22628B598

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

408-417

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM089745
Pays : United States

Informations de copyright

Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics.

Références

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Auteurs

Andrea Szabo (A)

Beecher-Mallinckrodt Laboratories, Department of Anesthesia Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Anahita Nourmahnad (A)

Beecher-Mallinckrodt Laboratories, Department of Anesthesia Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Elizabeth Halpin (E)

Beecher-Mallinckrodt Laboratories, Department of Anesthesia Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Stuart A Forman (SA)

Beecher-Mallinckrodt Laboratories, Department of Anesthesia Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts saforman@mgh.harvard.edu.

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Classifications MeSH