Prevalence and risk factors of anogenital human papillomavirus infection in a community sample of men who have sex with men in Taiwan: baseline findings from a cohort study.


Journal

Sexually transmitted infections
ISSN: 1472-3263
Titre abrégé: Sex Transm Infect
Pays: England
ID NLM: 9805554

Informations de publication

Date de publication:
02 2020
Historique:
received: 27 03 2018
revised: 30 11 2018
accepted: 04 01 2019
pubmed: 31 1 2019
medline: 29 4 2020
entrez: 31 1 2019
Statut: ppublish

Résumé

Men who have sex with men (MSM) are a highly neglected population in the current recommendation of girls-only human papillomavirus (HPV) vaccination programmes in many countries. To better assess the cost effectiveness of HPV vaccination among men requires data on the prevalence of HPV infection in MSM using a community sample, which is still sparse in several regions. We examined the prevalence of and factors associated with anogenital HPV infection among MSM in Taiwan. MSM 20 years of age and older were recruited from the community and social media in Taiwan in 2015-2016 and screened for HPV infection to detect 37 genotypes. MSM were seen at baseline and were/will be seen at 6, 12, 24 and 36 months. Men completed a questionnaire regarding their sexual experiences. Multivariable regression analyses were conducted to identify associated behavioural risk factors using the baseline data. A total of 253 MSM were recruited; 87 % were below 35 years of age. Diagnosis of HIV was reported in 4% of men; just over 20% had three or more anal sex partners in the past year. The prevalence of any tested HPV type was 29.4% at the anal site and 11% at the penile site. One quarter of MSM were infected with any of the 9-valent vaccine HPV types. Anal HPV detection was associated with having three or more receptive anal sex partners in the past year (adjusted odds ratio (aOR)=2.92, 95% CI 1.29 to 6.61) and having older sex partners (aOR=2.51, 95% CI 1.07 to 5.90). Our data provide the base to calculate the reproductive rate for HPV transmission in a low-risk community sample and cost-effectiveness to include men in HPV vaccination policies. Adding evidence from a community sample adds comprehensiveness for future estimates of disease transmission and vaccine effectiveness.

Identifiants

pubmed: 30696753
pii: sextrans-2018-053629
doi: 10.1136/sextrans-2018-053629
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

62-66

Informations de copyright

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Carol Strong (C)

Department of Public Health, College of Medicine, National Cheng Kung University Hospital, Tainan, Australia, Taiwan carol.chiajung@gmail.com.

Huachun Zou (H)

School of Public Health, Sun Yat-sen University, Shenzhen, Australia, China.
School of Public Health, Sun Yat-sen University, Guangzhou, Australia, China.
Kirby Institute, University of New South Wales, Sydney, Australia, Australia.

Nai-Ying Ko (NY)

Department of Public Health, College of Medicine, National Cheng Kung University Hospital, Tainan, Australia, Taiwan.
Department of Nursing, College of Medicine, National Cheng Kung University and Hospital, Tainan, Australia, Taiwan.
Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Australia, Taiwan.

Ya-Lun Liang (YL)

Department of Public Health, College of Medicine, National Cheng Kung University Hospital, Tainan, Australia, Taiwan.

Wen-Wei Ku (WW)

Division of Infectious Diseases, Taipei Veterans General Hospital, Taipei, Australia, Taiwan.

Chia-Wen Lee (CW)

Fengshan Lee Chia Wen Urologic Clinic, Kaohsiung, Australia, Taiwan.

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