Brexpiprazole for the maintenance treatment of adults with schizophrenia: an evidence-based review and place in therapy.

akathisia atypical antipsychotics relapse prevention second-generation antipsychotics weight gain

Journal

Neuropsychiatric disease and treatment
ISSN: 1176-6328
Titre abrégé: Neuropsychiatr Dis Treat
Pays: New Zealand
ID NLM: 101240304

Informations de publication

Date de publication:
2019
Historique:
entrez: 31 1 2019
pubmed: 31 1 2019
medline: 31 1 2019
Statut: epublish

Résumé

The purpose of this review is to describe the available data for brexpiprazole in the maintenance treatment of schizophrenia. This objective was completed by searching the databases PubMed, Embase, and ClinicalTrials.gov to identify relevant study results presented as papers or abstracts. In summary, brexpiprazole is a new agent in the D

Identifiants

pubmed: 30697049
doi: 10.2147/NDT.S169369
pii: ndt-15-247
pmc: PMC6339638
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

247-257

Déclaration de conflit d'intérêts

Disclosure No external funding or writing assistance from any source was used in the creation of this review. The manufacturer (Otsuka/ Lundbeck) had no involvement in terms of funding or review of this manuscript. KW has no disclosures to report. In the past 12 months, LC has acted as a consultant for Acadia, Alkermes, Allergan, Intra-Cellular Therapies, Janssen, Lundbeck, Merck, Neurocrine, Noven, Otsuka, Pfizer, Shire, Sunovion, Takeda, Teva, and Vanda; as a speaker for Acadia, Alkermes, Allergan, Janssen, Lundbeck, Merck, Neurocrine, Otsuka, Pfizer, Shire, Sunovion, Takeda, and Teva; and has received royalties from Wiley (editor-in-chief, International Journal of Clinical Practice), UpToDate (reviewer), and Springer Healthcare (book). LC holds stocks (small number of shares of common stock) in Bristol-Myers Squibb, Eli Lilly, Johnson & Johnson, Merck, and Pfizer (purchased more than 10 years ago). The authors report no other conflicts of interest in this work.

Références

PLoS One. 2014 Apr 24;9(4):e94112
pubmed: 24763306
J Pharmacol Exp Ther. 2014 Sep;350(3):589-604
pubmed: 24947465
Schizophr Res. 2015 May;164(1-3):127-35
pubmed: 25682550
Am J Psychiatry. 2015 Sep 1;172(9):870-80
pubmed: 25882325
Int J Clin Pract. 2015 Sep;69(9):978-97
pubmed: 26250067
J Clin Psychiatry. 2015 Sep;76(9):1224-31
pubmed: 26301701
J Clin Psychiatry. 2015 Sep;76(9):1232-40
pubmed: 26301771
Expert Rev Neurother. 2015 Oct;15(10):1219-29
pubmed: 26402059
Int J Clin Pract. 2015 Nov;69(11):1211-20
pubmed: 26477545
J Psychopharmacol. 2016 Jan;30(1):69-77
pubmed: 26645209
Int Clin Psychopharmacol. 2016 Jul;31(4):192-201
pubmed: 26963842
CNS Spectr. 2016 Oct;21(5):393-402
pubmed: 27048911
Schizophr Res. 2016 Oct;176(2-3):264-271
pubmed: 27427558
Int J Neuropsychopharmacol. 2017 Jan 1;20(1):11-21
pubmed: 27566723
Ther Adv Psychopharmacol. 2017 Jan;7(1):29-41
pubmed: 28101322
J Clin Psychopharmacol. 2017 Apr;37(2):138-147
pubmed: 28141623
Int J Neuropsychopharmacol. 2018 May 1;21(5):433-441
pubmed: 29415258
Psychiatry Clin Neurosci. 2018 Jun;72(6):445-453
pubmed: 29582518
J Comp Eff Res. 2018 Apr 26;:null
pubmed: 29697278
Psychiatry Clin Neurosci. 2018 Sep;72(9):692-700
pubmed: 29774628
Int Clin Psychopharmacol. 2018 Sep;33(5):255-260
pubmed: 29878915
Curr Med Res Opin. 2018 Dec;34(12):2197-2205
pubmed: 29985680
Int J Geriatr Psychiatry. 2018 Oct;33(10):1403-1410
pubmed: 30039634
Clinicoecon Outcomes Res. 2018 Aug 16;10:443-456
pubmed: 30147350
CNS Spectr. 2018 Oct 11;:1-11
pubmed: 30306884
J Clin Psychopharmacol. 2019 Jan/Feb;39(1):13-19
pubmed: 30566415

Auteurs

Kristen Ward (K)

Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI, USA.

Leslie Citrome (L)

Department of Psychiatry and Behavioral Science, New York Medical College, Valhalla, NY, USA, citrome@cnsconsultant.com.

Classifications MeSH