Safety and Pharmacokinetics of Standardized Extract of Centella asiatica (ECa 233) Capsules in Healthy Thai Volunteers: A Phase 1 Clinical Study.

Adolescent Adult Capsules Centella / chemistry Female Humans Male Middle Aged Plant Extracts Triterpenes / administration & dosage Young Adult

Journal

Planta medica
ISSN: 1439-0221
Titre abrégé: Planta Med
Pays: Germany
ID NLM: 0066751

Informations de publication

Date de publication:
Apr 2019
Historique:
pubmed: 31 1 2019
medline: 17 4 2019
entrez: 31 1 2019
Statut: ppublish

Résumé

The aim of this study was to investigate the safety and pharmacokinetic profiles of a newly developed, standardized extract of

Identifiants

DOI: 10.1055/a-0835-6671 PMID: 30699457
pubmed: 30699457
doi: 10.1055/a-0835-6671
doi:

Substances chimiques

Capsules 0
Centella asiatica extract 0
Plant Extracts 0
Triterpenes 0

Types de publication

Clinical Trial, Phase I Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

483-490

Informations de copyright

Georg Thieme Verlag KG Stuttgart · New York.

Déclaration de conflit d'intérêts

All authors declare no conflicts of interest.

Auteurs

Phanit Songvut (P)

Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.

Pajaree Chariyavilaskul (P)

Clinical Pharmacokinetics and Pharmacogenomics Research Unit, Department of Pharmacology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Mayuree H Tantisira (MH)

Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand.

Phisit Khemawoot (P)

Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Preclinical Pharmacokinetics and Interspecies Scaling for Drug Development Research Unit, Chulalongkorn University, Bangkok, Thailand.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Safety and Pharmacokinetics of Standardized...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Safety and Pharmacokinetics of Standardized...
questionsmedicales.fr › Préparations pharmaceutiques › Capsules › Safety and Pharmacokinetics of Standardized...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Apiaceae › Centella › Safety and Pharmacokinetics of Standardized...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Safety and Pharmacokinetics of Standardized...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Safety and Pharmacokinetics of Standardized...
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes › Safety and Pharmacokinetics of Standardized...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Triterpènes › Safety and Pharmacokinetics of Standardized...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Jeune adulte › Safety and Pharmacokinetics of Standardized...