Primary Sellar Paraganglioma: Case Report with Literature Review and Immunohistochemistry Resource.
Chromaffin
Glomus cell
Paraganglioma
Pathology
Pituitary adenoma
Sella
Journal
World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
29
09
2018
revised:
07
01
2019
accepted:
09
01
2019
pubmed:
1
2
2019
medline:
24
10
2019
entrez:
1
2
2019
Statut:
ppublish
Résumé
Differential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Primary paraganglioma is seldom considered. We present a case of this unique pathology, review the relevant literature, and compile a compendium of immunohistochemical characteristics for use as a resource. A 73-year-old woman presented to the hospital with visual changes in her left hemifield. Noncontrast head computed tomography demonstrated a large sellar mass with suprasellar extension and displacement of the optic chiasm (diameter of 3.1 cm). Magnetic resonance imaging was unobtainable owing to an incompatible pacemaker. Computed tomography characterization was most consistent with a macroadenoma. Given the acute visual decline, surgical decompression via an endonasal transsphenoidal route was performed without complication. A diagnosis of paraganglioma was made based on histopathology. Following resection, the patient's visual field deficit improved. Computed tomography body imaging was negative for a metastatic origin. Paraganglioma is a rare but potential differential diagnosis to consider when evaluating sellar masses.
Sections du résumé
BACKGROUND
Differential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Primary paraganglioma is seldom considered. We present a case of this unique pathology, review the relevant literature, and compile a compendium of immunohistochemical characteristics for use as a resource.
CASE DESCRIPTION
A 73-year-old woman presented to the hospital with visual changes in her left hemifield. Noncontrast head computed tomography demonstrated a large sellar mass with suprasellar extension and displacement of the optic chiasm (diameter of 3.1 cm). Magnetic resonance imaging was unobtainable owing to an incompatible pacemaker. Computed tomography characterization was most consistent with a macroadenoma. Given the acute visual decline, surgical decompression via an endonasal transsphenoidal route was performed without complication. A diagnosis of paraganglioma was made based on histopathology. Following resection, the patient's visual field deficit improved. Computed tomography body imaging was negative for a metastatic origin.
CONCLUSIONS
Paraganglioma is a rare but potential differential diagnosis to consider when evaluating sellar masses.
Identifiants
pubmed: 30703592
pii: S1878-8750(19)30192-5
doi: 10.1016/j.wneu.2019.01.094
pii:
doi:
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
32-36Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.