Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis.
Case report
Endoscopy
Enteropathy associated T-cell lymphoma
Gastrointestinal lymphoma
Literature review
Monomorphic epitheliotropic intestinal T-cell lymphoma
Peripheral T-cell lymphoma
Journal
World journal of gastrointestinal endoscopy
ISSN: 1948-5190
Titre abrégé: World J Gastrointest Endosc
Pays: United States
ID NLM: 101532474
Informations de publication
Date de publication:
16 Jan 2019
16 Jan 2019
Historique:
received:
20
11
2018
revised:
27
12
2018
accepted:
08
01
2019
entrez:
2
2
2019
pubmed:
2
2
2019
medline:
2
2
2019
Statut:
ppublish
Résumé
Enteropathy associated T-cell lymphoma (EATL) is a rare form of peripheral T-cell lymphoma and makes up less than 5% of gastrointestinal lymphomas. EATL can be divided into type 1 which is associated with celiac disease, and monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL), formally type 2, which is not associated with celiac disease. We present a 60-year-old African American female, without celiac disease, who presented with abdominal pain, diarrhea, and 30 lb. weight loss over a 3 month period. She was subsequently diagnosed with EATL throughout her entire gastrointestinal tract. She is currently undergoing chemotherapy with EOCH (Etoposide, Oncovin, Cyclophosphamide, and Hydroxydaunorubicin). EATL is most common in the Asian and Hispanic population yet the incidence in African Americans is uncertain and emphasizes the rarity of this case. A literature review was included to further emphasize similarities and differences between our case and previously reported cases of MEITL. The patient was diagnosed with EATL, immunochemical testing was not conclusive for MEITL however was suggestive of the disease.
Sections du résumé
BACKGROUND
BACKGROUND
Enteropathy associated T-cell lymphoma (EATL) is a rare form of peripheral T-cell lymphoma and makes up less than 5% of gastrointestinal lymphomas. EATL can be divided into type 1 which is associated with celiac disease, and monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL), formally type 2, which is not associated with celiac disease.
CASE SUMMARY
METHODS
We present a 60-year-old African American female, without celiac disease, who presented with abdominal pain, diarrhea, and 30 lb. weight loss over a 3 month period. She was subsequently diagnosed with EATL throughout her entire gastrointestinal tract. She is currently undergoing chemotherapy with EOCH (Etoposide, Oncovin, Cyclophosphamide, and Hydroxydaunorubicin). EATL is most common in the Asian and Hispanic population yet the incidence in African Americans is uncertain and emphasizes the rarity of this case. A literature review was included to further emphasize similarities and differences between our case and previously reported cases of MEITL.
CONCLUSION
CONCLUSIONS
The patient was diagnosed with EATL, immunochemical testing was not conclusive for MEITL however was suggestive of the disease.
Identifiants
pubmed: 30705732
doi: 10.4253/wjge.v11.i1.54
pmc: PMC6354114
doi:
Types de publication
Case Reports
Langues
eng
Pagination
54-60Déclaration de conflit d'intérêts
Conflict-of-interest statement: Dr. Aaron Fisher, Edward Yousif, and Marc Piper have no relevant conflicts of interest to disclose.
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