Visual outcome following phacoemulsification in English Cocker Spaniels with suspected progressive retinal atrophy: A retrospective multicenter study of 54 cases (2002-2017).


Journal

Veterinary ophthalmology
ISSN: 1463-5224
Titre abrégé: Vet Ophthalmol
Pays: England
ID NLM: 100887377

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 06 04 2018
revised: 29 09 2018
accepted: 25 10 2018
pubmed: 2 2 2019
medline: 28 1 2020
entrez: 2 2 2019
Statut: ppublish

Résumé

To describe the visual outcome following phacoemulsification in English Cocker Spaniels (ECS) affected by cataracts and suspected progressive retinal atrophy (PRA). Fifty-four client-owned dogs. A multicenter, retrospective study was performed including ECS with suspected PRA which underwent phacoemulsification. PRA was suspected on ophthalmic examination before and after surgery, and/or after electroretinography (ERG) was performed. Visual outcome was assessed by menace response per eye at seven time periods post-surgery (P1= 25-90 days, P2 = 91-180 days, P3 = 181-364 days, P4 = 365-549 days, P5 = 550-729 days, P6 = 730-1094 days, and P7 ≥ 1095 days). Descriptive statistics were performed. Generalized estimating equations were used to identify predictors associated with vision after surgery. Odds ratio and confidence intervals were reported. Significance was set at P < 0.05. Owners were invited to participate in a questionnaire. Phacoemulsification was performed in 85 eyes. Median age at surgery was 9.09 years (min. 2.17 years, max. 13.49 years). At all re-examinations, up to and including P5, significantly more eyes were visual than before surgery (P ≤ 0.003). Odds for vision were significantly increased for eyes that underwent surgery. Electroretinograms were performed in 75/85 eyes that underwent surgery, demonstrating low b-wave amplitudes. There was no significant effect of the age, gender, vision before surgery, presence of dazzle reflex, cataract stage or abnormality on gonioscopy on visual outcome. The questionnaire response rate was 48.2%. Most participants (92.5%) felt that cataract surgery led to improvement of the dog's quality of life. English Cocker Spaniels with suspected PRA may benefit from phacoemulsification with vision up to 2 years following surgery.

Identifiants

pubmed: 30706615
doi: 10.1111/vop.12627
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

591-599

Informations de copyright

© 2019 American College of Veterinary Ophthalmologists.

Références

Van Der Woerdt A, Nasisse MP, Davidson MG. Lens-induced uveitis in dogs: 151 cases (1985-1990). J Am Vet Med Assoc. 1992;201(6):921-926.
Van Der Woerdt A. Lens-induced uveitis. Vet Ophthalmol. 2000;3(4):227-234.
Lim CC, Bakker SC, Waldner CL, Sandmeyer LS, GrahnBH. Cataracts in 44 dogs (77 eyes): a comparison of outcomes for no treatment, topical medical management, or phacoemulsification with intraocular lens implantation. Can Vet J. 2011;52(3):283-288.
Klein HE, Krohne SG, Moore GE, Stiles J. Postoperative complications and visual outcomes of phacoemulsification in 103 dogs (179 eyes): 2006-2008. Vet Ophthalmol. 2011;14(2):114-120.
Davidson MG, Nasisse MP, Rusnak IM, Corbett WT, English RV. Success rates of unilateral vs. bilateral cataract extraction in dogs. Vet Surg. 1990;19(3):232-236.
Miller TR, Whitley RD, Meek LA, Garcia GA, Wilson MC, Rawls B. Phacofragmentation and aspiration for cataract extraction in dogs: 56 cases (1980-1984). J Am Vet Med Assoc. 1987;190(12):1577-1580.
Lannek EB, Miller PE. Development of glaucoma after phacoemulsification for removal of cataracts in dogs: 22 cases (1987-1997). J Am Vet Med Assoc. 2001;218(1):70-76.
Sigle KJ, Nasisse MP. Long-term complications after phacoemulsification for cataract removal in dogs: 172 cases (1995-2002). J Am Vet Med Assoc. 2006;228(1):74-79.
Yi NY, Park SA, Jeong M-B, et al. Phacoemulsification and acryl foldable intraocular lens implantation in dogs: 32 cases. J Vet Sci. 2006;7(3):281-285.
Curtis R. Retinal diseases in the dog and cat: an overview and update. J Small Anim Pract. 1988;29(7):397-415.
Barnett KC. Abnormalities and defects in pedigree dogs-IV. Progressive retinal atrophy. J Small Anim Pract. 1963;4(6):465-467.
Park SA, Yi NY, Jeong M-B, et al. Clinical manifestations of cataracts in small breed dogs. Vet Ophthalmol. 2009;12(4):205-210.
Donzel E, Arti L, Chahory S. Epidemiology and clinical presentation of canine cataracts in France: a retrospective study of 404 cases. Vet Ophthalmol. 2017;20(2):131-139.
Barnett KC. The diagnosis and differential diagnosis of cataract in the dog. J Small Anim Pract. 1985;26:305-316.
Adkins EA, Hendrix D. Outcomes of dogs presented for cataract evaluation. A retrospective study. J Am Anim Hosp Assoc. 2005;41(4):235-240.
Downs LM, Hitti R, Pregnolato S, Mellersh CS. Genetic screening for PRA-associated mutations in multiple dog breeds shows that PRA is heterogeneous within and between breeds. Vet Ophthalmol. 2014;17(2):126-130.
Narfström K, Petersen-Jones S. Diseases of the canine ocular fundus. 5th edn. In: Gelatt KN, Gilger BC, Kern TJ, eds. Veterinary Ophthalmology; 2013:90.
Miyadera K, Acland GM, Aguirre GD. Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mamm Genome. 2011;23(1-2):40-61.
Aguirre GD, Acland GM. Variation in retinal degeneration phenotype inherited at the PRCD locus. Exp Eye Res. 1988;46(5):663-687.
Davidson MG, Nelms SR. Diseases of the lens and cataract formation. In: Gelatt KN, Gilger BC, Kern TJ, eds. Veterinary Ophthalmology. 5th edn. Hoboken, NJ: Wiley-Blackwell;2013:35.
Dostal J, Hrdlicova A. Progressive rod-cone degeneration (PRCD) in selected dog breeds and variability in its phenotypic expression. Vet Med. 2011;56:243-247.
Komáromy AM, Brooks DE, Dawson WW, Källberg ME, Ollivier FJ, Ofri R. Technical issues in electrodiagnostic recording. Vet Ophthalmol. 2002;5(2):85-91.
Maehara S, Itoh N, Wakaiki S, Yamasaki A, Tsuzuki K, Izumisawa Y. The effects of cataract stage, lens-induced uveitis and cataract removal on ERG in dogs with cataract. Vet Ophthalmol. 2007;10(5):308-312.
Freeman KS, Good KL, Kass PH, Park SA, Nestorowicz N, Ofri R. Effects of chemical restraint on electroretinograms recorded sequentially in awake, sedated, and anesthetized dogs. Am J Vet Res. 2013;74(7):1036-1042.
Narfström K, Ekesten B, Rosolen SG, et al. Guidelines for clinical electroretinography in the dog. Doc Ophthalmol. 2002;83-92.
Ekesten B, Komáromy AM, Ofri R, Petersen-Jones SM, Narfström K. Guidelines for clinical electroretinography in the dog: 2012 update. Doc Ophthalmol. 2013;127(2):79-87.
Kleinmann G, Hoffman P, Schechtman E, Pollack A. Microscope-induced retinal phototoxicity in cataract surgery of short duration. Ophthalmology. 2002;109(2):334-338.
Michael R, Wegener A. Estimation of safe exposure time from an ophthalmic operating microscope with regard to ultraviolet radiation and blue-light hazards to the eye. J Opt Soc Am. 2004;21(8):1388-1392.
Baruch Y. Response rate in academic studies - a comparative analysis. Hum Relat. 1999;52(4):421-438.

Auteurs

Sarah Koll-Hampp (S)

Ophthalmology Service, Royal Veterinary College (RVC), University of London, North Mymms, UK.

Andra-Elena Enache (AE)

Unit of Comparative Ophthalmology, Animal Health Trust (AHT), Newmarket, UK.

Elena Fenollosa-Romero (E)

Ophthalmology Service, Dick White Referrals (DWR), Six Mile Bottom, UK.

Yu-Mei Chang (YM)

Ophthalmology Service, Royal Veterinary College (RVC), University of London, North Mymms, UK.

Claudia Busse (C)

Ophthalmology Service, Dick White Referrals (DWR), Six Mile Bottom, UK.

James Oliver (J)

Unit of Comparative Ophthalmology, Animal Health Trust (AHT), Newmarket, UK.

Charlotte Dawson (C)

Ophthalmology Service, Royal Veterinary College (RVC), University of London, North Mymms, UK.

Màrian Matas Riera (M)

Ophthalmology Service, Royal Veterinary College (RVC), University of London, North Mymms, UK.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male
Humans Meals Time Factors Female Adult

Classifications MeSH