Delay differential analysis for dynamical sleep spindle detection.


Journal

Journal of neuroscience methods
ISSN: 1872-678X
Titre abrégé: J Neurosci Methods
Pays: Netherlands
ID NLM: 7905558

Informations de publication

Date de publication:
15 03 2019
Historique:
received: 16 05 2018
revised: 04 01 2019
accepted: 20 01 2019
pubmed: 2 2 2019
medline: 29 7 2020
entrez: 2 2 2019
Statut: ppublish

Résumé

Sleep spindles are involved in memory consolidation and other cognitive functions. Numerous automated methods for detection of spindles have been proposed; most of these rely on spectral analysis in some form. However, none of these approaches are ideal, and novel approaches to the problem could provide additional insights. Here, we apply delay differential analysis (DDA), a time-domain technique based on nonlinear dynamics to detect sleep spindles in human intracranial sleep data, including laminar electrode, stereoelectroencephalogram (sEEG), and electrocorticogram (ECoG) recordings. We show that this approach is computationally fast, generalizable, requires minimal preprocessing, and provides excellent agreement with human scoring. We compared the method with established methods on a set of intracranial recordings and this method provided the highest agreement with human expert scoring when evaluated with F This additional, non-frequency-based perspective could prove particularly useful for certain atypical spindles, or identifying spindles of different types.

Sections du résumé

BACKGROUND
Sleep spindles are involved in memory consolidation and other cognitive functions. Numerous automated methods for detection of spindles have been proposed; most of these rely on spectral analysis in some form. However, none of these approaches are ideal, and novel approaches to the problem could provide additional insights.
NEW METHOD
Here, we apply delay differential analysis (DDA), a time-domain technique based on nonlinear dynamics to detect sleep spindles in human intracranial sleep data, including laminar electrode, stereoelectroencephalogram (sEEG), and electrocorticogram (ECoG) recordings.
RESULTS
We show that this approach is computationally fast, generalizable, requires minimal preprocessing, and provides excellent agreement with human scoring.
COMPARISON WITH EXISTING METHODS
We compared the method with established methods on a set of intracranial recordings and this method provided the highest agreement with human expert scoring when evaluated with F
CONCLUSIONS
This additional, non-frequency-based perspective could prove particularly useful for certain atypical spindles, or identifying spindles of different types.

Identifiants

pubmed: 30707917
pii: S0165-0270(19)30020-2
doi: 10.1016/j.jneumeth.2019.01.009
pmc: PMC6447286
mid: NIHMS1521353
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

12-21

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB009282
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS104368
Pays : United States
Organisme : NIMH NIH HHS
ID : T32 MH020002
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB026899
Pays : United States
Organisme : NINDS NIH HHS
ID : F99 NS105204
Pays : United States

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

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Auteurs

Aaron L Sampson (AL)

Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Neurosciences Graduate Program, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: asampson@ucsd.edu.

Claudia Lainscsek (C)

Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Institute for Neural Computation, University of California San Diego, La Jolla, CA 92093, USA.

Christopher E Gonzalez (CE)

Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Neurosciences Graduate Program, University of California San Diego, La Jolla, CA 92093, USA.

István Ulbert (I)

Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2, H-1117 Budapest, Hungary; Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, H-1083 Budapest, Hungary.

Orrin Devinsky (O)

New York University Comprehensive Epilepsy Center, New York, NY 10016, USA.

Dániel Fabó (D)

Epilepsy Centrum, National Institute of Clinical Neurosciences, Budapest, Hungary.

Joseph R Madsen (JR)

Departments of Neurosurgery, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Eric Halgren (E)

Departments of Radiology and Neurosciences, University of California San Diego, La Jolla, CA 92093, USA.

Sydney S Cash (SS)

Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, MA 02114, USA.

Terrence J Sejnowski (TJ)

Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Institute for Neural Computation, University of California San Diego, La Jolla, CA 92093, USA; Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.

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Classifications MeSH