Update on Myogenic Sarcomas.
Alveolar
Embryonal
FOXO1
Leiomyosarcoma
MYOD1
Pleomorphic
Rhabdomyosarcoma
Spindle cell/Sclerosing
Journal
Surgical pathology clinics
ISSN: 1875-9157
Titre abrégé: Surg Pathol Clin
Pays: United States
ID NLM: 101491209
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
entrez:
3
2
2019
pubmed:
3
2
2019
medline:
1
6
2019
Statut:
ppublish
Résumé
Myogenic sarcomas include soft tissue sarcomas that show skeletal muscle differentiation (rhabdomyosarcoma) and those with smooth muscle differentiation (leiomyosarcoma). Rhabdomyosarcomas are more common in the pediatric age group and leiomyosarcomas occur more often in the adult population. Based on the clinico-pathologic features and genetic abnormalities identified, the rhabdomyosarcomas are classified into embryonal, alveolar, spindle cell/sclerosing, and pleomorphic subtypes. Each subtype shows distinctive morphology and has characteristic genetic abnormalities. In this update on myogenic sarcomas, each entity is discussed with special emphasis on recent updates in genetic findings and the diagnostic approach to these tumors.
Identifiants
pubmed: 30709448
pii: S1875-9181(18)30066-7
doi: 10.1016/j.path.2018.10.003
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
MyoD Protein
0
MyoD1 myogenic differentiation protein
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
51-62Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.