A theoretical framework for planar polarity establishment through interpretation of graded cues by molecular bridges.
Asymmetry
Gradient
Mathematical modelling
Patterning
Planar cell polarity (PCP)
Planar polarity
Journal
Development (Cambridge, England)
ISSN: 1477-9129
Titre abrégé: Development
Pays: England
ID NLM: 8701744
Informations de publication
Date de publication:
01 02 2019
01 02 2019
Historique:
entrez:
3
2
2019
pubmed:
3
2
2019
medline:
24
10
2019
Statut:
epublish
Résumé
Planar polarity is a widespread phenomenon found in many tissues, allowing cells to coordinate morphogenetic movements and function. A common feature of animal planar polarity systems is the formation of molecular bridges between cells, which become polarised along a tissue axis. We propose that these bridges provide a general mechanism by which cells interpret different forms of tissue gradients to coordinate directional information. We illustrate this using a generalised and consistent modelling framework, providing a conceptual basis for understanding how different mechanisms of gradient function can generate planar polarity. We make testable predictions of how different gradient mechanisms can influence polarity direction.
Identifiants
pubmed: 30709912
pii: 146/3/dev168955
doi: 10.1242/dev.168955
pmc: PMC6382004
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R016925/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 100986/Z/13/Z
Pays : United Kingdom
Informations de copyright
© 2019. Published by The Company of Biologists Ltd.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare no competing or financial interests.
Références
Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20420-5
pubmed: 24282293
Dev Cell. 2011 Feb 15;20(2):163-76
pubmed: 21316585
Curr Biol. 2012 Jul 24;22(14):1302-8
pubmed: 22727698
Development. 1995 Sep;121(9):3045-55
pubmed: 7555730
Nat Cell Biol. 2008 Nov;10(11):1257-68
pubmed: 18849982
Curr Biol. 2016 Aug 22;26(16):2090-100
pubmed: 27451904
Development. 2004 Feb;131(4):881-90
pubmed: 14757640
Dev Biol. 1996 Feb 1;173(2):428-46
pubmed: 8606003
Curr Opin Cell Biol. 2017 Feb;44:110-116
pubmed: 27576155
Science. 2012 May 11;336(6082):724-7
pubmed: 22499807
Nature. 1987 Oct 8-14;329(6139):549-51
pubmed: 3116434
Cell Res. 2017 Dec;27(12):1466-1484
pubmed: 29056748
Development. 2004 Aug;131(15):3785-94
pubmed: 15240556
Cell. 2010 Sep 3;142(5):773-86
pubmed: 20813263
Nature. 2003 Jan 30;421(6922):543-7
pubmed: 12540853
Wiley Interdiscip Rev Syst Biol Med. 2011 Sep-Oct;3(5):588-605
pubmed: 21755606
Development. 2018 Dec 10;145(23):
pubmed: 30530515
Curr Biol. 2017 Sep 25;27(18):2784-2797.e3
pubmed: 28918952
Cell. 1999 Sep 3;98(5):585-95
pubmed: 10490098
Curr Biol. 1997 Dec 1;7(12):940-9
pubmed: 9382848
PLoS Comput Biol. 2009 Dec;5(12):e1000628
pubmed: 20041171
Development. 2011 May;138(10):1877-92
pubmed: 21521735
Annu Rev Cell Dev Biol. 2011;27:377-407
pubmed: 21801015
Mol Cell. 2001 Feb;7(2):367-75
pubmed: 11239465
Development. 2017 Jan 15;144(2):187-200
pubmed: 28096212
Nat Cell Biol. 2013 Sep;15(9):1045-55
pubmed: 23912125
Cold Spring Harb Perspect Biol. 2009 Nov;1(5):a000489
pubmed: 20066114
PLoS One. 2013 Apr 08;8(4):e60064
pubmed: 23593163
Science. 2005 Jan 21;307(5708):423-6
pubmed: 15662015
Development. 1999 Dec;126(23):5421-9
pubmed: 10556066
Curr Biol. 2010 May 11;20(9):811-7
pubmed: 20434335
Curr Biol. 1999 Dec 2;9(23):1363-72
pubmed: 10607560
Cell. 2008 Jun 13;133(6):1093-105
pubmed: 18555784
Genes Dev. 1995 Jun 15;9(12):1530-42
pubmed: 7601355
Cell. 2002 May 3;109(3):371-81
pubmed: 12015986
Elife. 2017 Aug 18;6:
pubmed: 28826487
Nat Rev Genet. 2007 Jul;8(7):555-63
pubmed: 17563758
Curr Biol. 2010 May 11;20(9):803-10
pubmed: 20434337
Development. 2012 Oct;139(19):3665-74
pubmed: 22949620
Dev Dyn. 2006 Jan;235(1):235-46
pubmed: 16258926
Cell. 2002 Mar 8;108(5):675-88
pubmed: 11893338
Curr Biol. 2008 Oct 28;18(20):1555-64
pubmed: 18804371
Dev Growth Differ. 2017 Jan;59(1):41-51
pubmed: 28097650
Elife. 2015 Feb 24;4:
pubmed: 25707557
Curr Biol. 2012 May 22;22(10):907-14
pubmed: 22503504
Development. 2013 May;140(10):2061-74
pubmed: 23633507
Dev Biol. 2000 Dec 15;228(2):181-96
pubmed: 11112323
Elife. 2016 Sep 23;5:
pubmed: 27658614
Annu Rev Cell Biol. 1988;4:649-86
pubmed: 2848555
Nat Rev Mol Cell Biol. 2017 Jun;18(6):375-388
pubmed: 28293032
PLoS Genet. 2015 May 21;11(5):e1005259
pubmed: 25996914
Curr Opin Genet Dev. 2007 Aug;17(4):272-80
pubmed: 17627806
PLoS One. 2014 May 19;9(5):e97641
pubmed: 24841507
PLoS Comput Biol. 2013;9(12):e1003396
pubmed: 24348237
J Neurobiol. 2005 Sep 15;64(4):446-57
pubmed: 16041762
Development. 2004 Oct;131(19):4651-64
pubmed: 15329345
Development. 1995 Sep;121(9):2767-77
pubmed: 7555705
Dev Cell. 2008 Sep;15(3):462-9
pubmed: 18804440
Science. 2008 Jul 18;321(5887):401-4
pubmed: 18635802
Development. 2003 Jul;130(13):3007-14
pubmed: 12756182
Trends Genet. 1996 Sep;12(9):359-64
pubmed: 8855666
Cell Rep. 2016 Jul 12;16(2):344-356
pubmed: 27346358