Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer.

Animals Cell Line, Tumor ErbB Receptors / genetics Female Fibroblasts / metabolism Gene Expression Regulation, Neoplastic Humans Integrins / genetics Mice, Inbred NOD Mice, Transgenic Ovarian Neoplasms / genetics Peritoneal Neoplasms / pathology Spheroids, Cellular / pathology Xenograft Model Antitumor Assays

Journal

The Journal of experimental medicine
ISSN: 1540-9538
Titre abrégé: J Exp Med
Pays: United States
ID NLM: 2985109R

Informations de publication

Date de publication:
04 03 2019
Historique:
received: 24 04 2018
revised: 02 09 2018
accepted: 12 10 2018
pubmed: 3 2 2019
medline: 24 3 2020
entrez: 3 2 2019
Statut: ppublish

Résumé

High-grade serous ovarian cancer (HGSOC) is hallmarked by early onset of peritoneal dissemination, which distinguishes it from low-grade serous ovarian cancer (LGSOC). Here, we describe the aggressive nature of HGSOC ascitic tumor cells (ATCs) characterized by integrin α5

Identifiants

DOI: 10.1084/jem.20180765 PMID: 30710055 PMC: PMC6400537
pubmed: 30710055
pii: jem.20180765
doi: 10.1084/jem.20180765
pmc: PMC6400537
doi:

Substances chimiques

ITGA5 protein, human 0
Integrins 0
EGFR protein, human EC 2.7.10.1
ErbB Receptors EC 2.7.10.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

688-703

Commentaires et corrections

Type : CommentIn
Type : ErratumIn

Informations de copyright

© 2019 Gao et al.

Références

J Clin Invest. 2013 Jan;123(1):150-63
pubmed: 23241956
J Clin Invest. 2014 Oct;124(10):4614-28
pubmed: 25202979
Annu Rev Pathol. 2014;9:27-45
pubmed: 23937438
Cancer Res. 2011 Nov 1;71(21):6633-42
pubmed: 22009535
J Cell Biol. 2009 Jan 26;184(2):309-22
pubmed: 19171760
Expert Rev Anticancer Ther. 2015;15(8):893-9
pubmed: 26040191
Cancer Cell. 2002 Nov;2(5):353-61
pubmed: 12450790
Oncotarget. 2015 May 10;6(13):11530-46
pubmed: 25839165
BMC Cancer. 2011 May 30;11:210
pubmed: 21619709
Genome Res. 2009 Jul;19(7):1279-88
pubmed: 19470664
Carcinogenesis. 2011 Oct;32(10):1540-9
pubmed: 21859834
Nat Commun. 2014 Dec 09;5:5662
pubmed: 25489927
Cancer Res. 2014 Oct 1;74(19):5597-607
pubmed: 25142796
Cell. 2005 May 6;121(3):335-48
pubmed: 15882617
Int J Cancer. 2009 May 1;124(9):2060-70
pubmed: 19132753
Gynecol Oncol. 2012 Aug;126(2):279-85
pubmed: 22555104
J Biol Chem. 2008 May 9;283(19):13021-30
pubmed: 18339627
Proc Natl Acad Sci U S A. 2013 May 28;110(22):E1974-83
pubmed: 23645635
Nat Commun. 2015 Feb 05;6:6220
pubmed: 25653139
Am J Pathol. 2004 Dec;165(6):1955-67
pubmed: 15579439
Eur J Gynaecol Oncol. 2008;29(6):568-72
pubmed: 19115680
Cancer Cell. 2010 Feb 17;17(2):135-47
pubmed: 20138012
Clin Transl Oncol. 2014 Jul;16(7):668-74
pubmed: 24248895
Carcinogenesis. 2013 Sep;34(9):2137-44
pubmed: 23640047
Onco Targets Ther. 2015 Feb 23;8:471-85
pubmed: 25750541
Nat Med. 2011 Oct 30;17(11):1498-503
pubmed: 22037646
Mol Cancer Res. 2016 Mar;14(3):287-95
pubmed: 26631572
Cancer Metastasis Rev. 2014 Mar;33(1):17-39
pubmed: 24357056
Hum Cell. 2005 Sep;18(3):147-55
pubmed: 17022147
J Clin Invest. 2016 Nov 1;126(11):4157-4173
pubmed: 27721235
BMC Cancer. 2012 Aug 18;12:359
pubmed: 22901285
Int J Cancer. 2005 Apr 20;114(4):531-43
pubmed: 15609323
Cancer Discov. 2016 May;6(5):474-6
pubmed: 27138561
Cancer Discov. 2011 Jul;1(2):100-2
pubmed: 22013555
Cancer Res. 2008 Apr 1;68(7):2329-39
pubmed: 18381440
Nat Rev Cancer. 2013 Apr;13(4):273-82
pubmed: 23426401
Cancer Res. 2005 Apr 15;65(8):3025-9
pubmed: 15833827
Nat Rev Cancer. 2011 Sep 23;11(10):719-25
pubmed: 21941283
Mod Pathol. 2009 Sep;22(9):1243-50
pubmed: 19525924
Cancer Treat Res. 2009;149:335-51
pubmed: 19763444
Hum Pathol. 2015 Oct;46(10):1455-63
pubmed: 26232113
Bioinformatics. 2003 Dec 12;19(18):2448-55
pubmed: 14668230
Clin Cancer Res. 2008 Dec 1;14(23):7924-9
pubmed: 19047123
Cancer Treat Res. 2009;149:297-318
pubmed: 19763442
Nat Commun. 2014 Mar 25;5:3472
pubmed: 24668028
Cancer. 2008 Aug 15;113(4):723-32
pubmed: 18618737
PLoS One. 2012;7(10):e46858
pubmed: 23056490
Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21677-82
pubmed: 21098274
Oncogene. 2011 Mar 31;30(13):1566-76
pubmed: 21119598
Int J Gynecol Cancer. 2000 Jan;10(1):33-41
pubmed: 11240649
J Exp Med. 2015 Jul 27;212(8):1283-301
pubmed: 26195726
Front Oncol. 2013 Sep 25;3:256
pubmed: 24093089
Cancer Biol Ther. 2018;19(10):887-897
pubmed: 30067440
Int J Cancer. 2016 Oct 15;139(8):1788-98
pubmed: 27242346
Nat Protoc. 2013 Nov;8(11):2281-2308
pubmed: 24157548
Am J Pathol. 2010 Sep;177(3):1053-64
pubmed: 20651229
Nat Commun. 2015 Jun 17;6:7351
pubmed: 26081979
J Natl Cancer Inst. 2014 Sep 30;106(10):
pubmed: 25269487
Clin Exp Metastasis. 2000;18(1):67-75
pubmed: 11206841
Gynecol Oncol. 2011 May 1;121(2):273-9
pubmed: 21276608
Curr Oncol Rep. 2008 Nov;10(6):519-23
pubmed: 18928667
Mol Biol Cell. 2000 Sep;11(9):2885-900
pubmed: 10982388
Cancer Lett. 2017 Mar 1;388:158-166
pubmed: 27940126

Auteurs

Qinglei Gao (Q)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China qingleigao@hotmail.com.
ORCID: 0000-0002-9448-3423

Zongyuan Yang (Z)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Sen Xu (S)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Xiaoting Li (X)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Xin Yang (X)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Ping Jin (P)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Yi Liu (Y)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Xiaoshui Zhou (X)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Taoran Zhang (T)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Cheng Gong (C)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Xiao Wei (X)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Dan Liu (D)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Chaoyang Sun (C)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Gang Chen (G)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Junbo Hu (J)

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Li Meng (L)

Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Jianfeng Zhou (J)

Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Kenjiro Sawada (K)

Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Yamadaoka Suita, Osaka, Japan.

Robert Fruscio (R)

Clinic of Obstetrics and Gynecology, San Gerardo Hospital, Monza, Italy.
Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.
ORCID: 0000-0001-5688-2194

Thomas W Grunt (TW)

Signaling Networks Program, Division of Oncology, Department of Medicine I, Comprehensive Cancer Center & Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.

Jörg Wischhusen (J)

Department of Obstetrics and Gynecology, Experimental Tumor Immunology, University of Würzburg Medical School, Würzburg, Germany.

Víctor Manuel Vargas-Hernández (VM)

Dirección de Investigación, Hospital Juárez de México D.F., Nápoles, Mexico City, Mexico.
ORCID: 0000-0001-5461-2473

Bhavana Pothuri (B)

Division of Gynecological Oncology, NYU Langone Medical Center, Perlmutter Cancer Center, New York, NY.

Robert L Coleman (RL)

Department of Gynecological Oncology & Reproductive Medicine, University of Texas, M.D. Anderson Cancer Center, Houston, TX.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur facteur croissance › Récepteurs ErbB › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Fibroblastes › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes tumoraux › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Intégrines › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée NOD › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Maladies endocriniennes › Troubles gonadiques › Maladies ovariennes › Tumeurs de l'ovaire › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du péritoine › Tumeurs du péritoine › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Cellules › Cellules cultivées › Sphéroïdes de cellules › Heterotypic CAF-tumor spheroids promote early...
questionsmedicales.fr › Techniques d'investigation › Transplantation tumorale › Tests d'activité antitumorale sur modèle de xénogreffe › Heterotypic CAF-tumor spheroids promote early...