Exposure measurement error in air pollution studies: A framework for assessing shared, multiplicative measurement error in ensemble learning estimates of nitrogen oxides.


Journal

Environment international
ISSN: 1873-6750
Titre abrégé: Environ Int
Pays: Netherlands
ID NLM: 7807270

Informations de publication

Date de publication:
04 2019
Historique:
received: 07 09 2018
revised: 10 12 2018
accepted: 12 12 2018
pubmed: 4 2 2019
medline: 2 11 2019
entrez: 4 2 2019
Statut: ppublish

Résumé

Increasingly ensemble learning-based spatiotemporal models are being used to estimate residential air pollution exposures in epidemiological studies. While these machine learning models typically have improved performance, they suffer from exposure measurement error that is inherent in all models. Our objective is to develop a framework to formally assess shared, multiplicative measurement error (SMME) in our previously published three-stage, ensemble learning-based nitrogen oxides (NO By treating the ensembles as an external dosimetry system, we quantified shared and unshared, multiplicative and additive (SUMA) measurement error components in our exposure model. We used generalized additive models (GAMs) with a smooth term for location to identify geographic locations with significantly elevated SMME and explain their spatial and temporal determinants. We found evidence of significant shared and unshared multiplicative error (p < 0.0001) in our ensemble-learning based spatiotemporal NO We developed a novel statistical framework to formally evaluate the magnitude and drivers of SMME in ensemble learning-based exposure models. Our framework can be used to inform building future improved exposure models.

Sections du résumé

BACKGROUND
Increasingly ensemble learning-based spatiotemporal models are being used to estimate residential air pollution exposures in epidemiological studies. While these machine learning models typically have improved performance, they suffer from exposure measurement error that is inherent in all models. Our objective is to develop a framework to formally assess shared, multiplicative measurement error (SMME) in our previously published three-stage, ensemble learning-based nitrogen oxides (NO
METHODS
By treating the ensembles as an external dosimetry system, we quantified shared and unshared, multiplicative and additive (SUMA) measurement error components in our exposure model. We used generalized additive models (GAMs) with a smooth term for location to identify geographic locations with significantly elevated SMME and explain their spatial and temporal determinants.
RESULTS
We found evidence of significant shared and unshared multiplicative error (p < 0.0001) in our ensemble-learning based spatiotemporal NO
CONCLUSIONS
We developed a novel statistical framework to formally evaluate the magnitude and drivers of SMME in ensemble learning-based exposure models. Our framework can be used to inform building future improved exposure models.

Identifiants

pubmed: 30711654
pii: S0160-4120(18)32003-8
doi: 10.1016/j.envint.2018.12.025
pmc: PMC6499078
mid: NIHMS1520458
pii:
doi:

Substances chimiques

Air Pollutants 0
Nitrogen Oxides 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

97-106

Subventions

Organisme : NIEHS NIH HHS
ID : P30 ES007048
Pays : United States
Organisme : NIEHS NIH HHS
ID : P50 ES026086
Pays : United States
Organisme : NIBIB NIH HHS
ID : U54 EB022002
Pays : United States
Organisme : NIH HHS
ID : UH3 OD023287
Pays : United States

Informations de copyright

Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.

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Auteurs

Mariam S Girguis (MS)

Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: mgirguis@usc.edu.

Lianfa Li (L)

Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Fred Lurmann (F)

Sonoma Technology, Inc., Petaluma, CA, USA.

Jun Wu (J)

Department of Public Health, College of Health Sciences, University of California, Irvine, CA, USA.

Robert Urman (R)

Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Edward Rappaport (E)

Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Carrie Breton (C)

Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Frank Gilliland (F)

Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Daniel Stram (D)

Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Rima Habre (R)

Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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Classifications MeSH