The pathology and aetiology of subcortical clefts in infants.


Journal

Forensic science international
ISSN: 1872-6283
Titre abrégé: Forensic Sci Int
Pays: Ireland
ID NLM: 7902034

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 30 05 2018
revised: 12 11 2018
accepted: 11 01 2019
pubmed: 4 2 2019
medline: 15 3 2019
entrez: 4 2 2019
Statut: ppublish

Résumé

In infants, traumatic surface contusions of the brain are rare but subcortical clefts or cysts, variously labelled "contusional tears", "contusional clefts", "cortical tears" or "parenchymal lacerations" have been ascribed to trauma, and are even said to be characteristic of shaking and abuse. We describe the pathology of subcortical clefts or haemorrhages in seven infants. In none were the axonal swellings characteristic of traumatic axonal injury seen in relation to the clefts. Subpial bleeding was associated with clefts in all the cases of recent onset. We hypothesize that subcortical clefts are not due to direct mechanical forces of trauma but are part of a secondary cascade caused by impaired venous drainage which may or may not follow trauma. The finding of subcortical and subpial haemorrhages should prompt a search for CVT. We consider the term "contusion" is not accurate and is misleading.

Identifiants

pubmed: 30711846
pii: S0379-0738(19)30020-9
doi: 10.1016/j.forsciint.2019.01.011
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

115-122

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Karen Bonde Larsen (KB)

Department of Pathology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; Department of Neuropathology and Ocular Pathology, John Radcliffe Hospital, Oxford University Hospital, Oxford, United Kingdom. Electronic address: Karen.bonde.larsen.01@regionh.dk.

Zoe Barber (Z)

Department of General Surgery, Royal Gwent Hospital, Newport, United Kingdom.

Waney Squier (W)

Department of Neuropathology and Ocular Pathology, John Radcliffe Hospital, Oxford University Hospital, Oxford, United Kingdom.

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Classifications MeSH