Anticatabolic Effects of Ketone Bodies in Skeletal Muscle.
acetoacetate
atrophy
cachexia
inflammation
muscle protein breakdown
β-hydroxybutyrate
Journal
Trends in endocrinology and metabolism: TEM
ISSN: 1879-3061
Titre abrégé: Trends Endocrinol Metab
Pays: United States
ID NLM: 9001516
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
12
01
2019
accepted:
15
01
2019
pubmed:
5
2
2019
medline:
17
3
2020
entrez:
5
2
2019
Statut:
ppublish
Résumé
The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) are the subject of renewed interest given recently established pleiotropic effects regulating inflammation, oxidative stress, and gene expression. Anticatabolic effects of β-hydroxybutyrate have recently been demonstrated in human skeletal muscle under inflammatory insult, thereby expanding upon the wide-ranging therapeutic applications of nutritional ketosis.
Identifiants
pubmed: 30712977
pii: S1043-2760(19)30012-8
doi: 10.1016/j.tem.2019.01.006
pii:
doi:
Substances chimiques
Acetoacetates
0
Ketone Bodies
0
acetoacetic acid
4ZI204Y1MC
3-Hydroxybutyric Acid
TZP1275679
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
227-229Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.