Positron Emission Tomography-Computed Tomography in a Case of POEMS Syndrome.
18F-fluorodeoxyglucose
POEMS syndrome
osteolytic lesion
positron emission tomography-computed tomography
Journal
Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
ISSN: 0972-3919
Titre abrégé: Indian J Nucl Med
Pays: India
ID NLM: 8901274
Informations de publication
Date de publication:
Historique:
entrez:
5
2
2019
pubmed:
5
2
2019
medline:
5
2
2019
Statut:
ppublish
Résumé
The POEMS syndrome is a rare and multisystemic disease characterized by the presence of polyneuropathy, organomegaly, endocrinopathy, presence of M protein, and alterations in the skin. The existence of bone lesions is frequent, being generally blastic or mixed and rarely lytic. We present the case of a 54-year-old male patient diagnosed with POEMS syndrome, with atypical presence of lytic lesions, who was referred for an 18F-fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT) study for initial staging of the process. There were several hypermetabolic foci coinciding with bone lesions, reaching a maximum standardized uptake value of 15 at the level of the right iliac bone with associated soft-tissue mass. PET-CT is an adequate tool for evaluation, diagnosis, and monitoring of the pathology. The scan allows the detection and selection for its biopsy of bone lesions and lymphadenopathies.
Identifiants
pubmed: 30713387
doi: 10.4103/ijnm.IJNM_120_18
pii: IJNM-34-66
pmc: PMC6352633
doi:
Types de publication
Case Reports
Langues
eng
Pagination
66-68Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
Blood. 2003 Apr 1;101(7):2496-506
pubmed: 12456500
J Radiol. 2003 Apr;84(4 Pt 1):393-7
pubmed: 12759653
Brain. 2005 Aug;128(Pt 8):1911-20
pubmed: 15975949
Eur J Radiol. 2010 Nov;76(2):180-2
pubmed: 19581061
Lancet Oncol. 2014 Nov;15(12):e538-48
pubmed: 25439696
J Nucl Med. 2015 Sep;56(9):1334-7
pubmed: 26182964
Int J Clin Exp Med. 2015 May 15;8(5):7467-76
pubmed: 26221290
Skeletal Radiol. 2017 Jun;46(6):817-823
pubmed: 28343327
Hematol Oncol Clin North Am. 2018 Feb;32(1):119-139
pubmed: 29157614
Hematol Oncol Clin North Am. 2018 Feb;32(1):141-151
pubmed: 29157615