A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Journal
Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951
Informations de publication
Date de publication:
07 Jan 2019
07 Jan 2019
Historique:
received:
06
03
2018
accepted:
03
10
2018
entrez:
5
2
2019
pubmed:
5
2
2019
medline:
5
2
2019
Statut:
epublish
Résumé
Inteins remove themselves from a precursor protein by protein splicing. Due to the concomitant structural changes of the host protein, this self-processing reaction has enabled many applications in protein biotechnology and chemical biology. We show that the evolved M86 mutant of the
Identifiants
pubmed: 30713635
doi: 10.1039/c8sc01074a
pii: c8sc01074a
pmc: PMC6333167
doi:
Types de publication
Journal Article
Langues
eng
Pagination
239-251Références
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