Convenient Access to Chiral Cyclobutanes with Three Contiguous Stereocenters from Verbenone by Directed C(sp
8-aminoquinoline
C(sp3)−H functionalization
cyclobutanes
palladium
verbenone
Journal
Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Titre abrégé: Chemistry
Pays: Germany
ID NLM: 9513783
Informations de publication
Date de publication:
05 Apr 2019
05 Apr 2019
Historique:
received:
27
12
2018
pubmed:
5
2
2019
medline:
5
2
2019
entrez:
5
2
2019
Statut:
ppublish
Résumé
This work demonstrates how a series of complex, chiral cyclobutane derivatives can be accessed in four steps from the terpene verbenone through the application of a directed C-H functionalization approach. The developed synthetic route involved an 8-aminoquinoline-directed C(sp
Identifiants
pubmed: 30716181
doi: 10.1002/chem.201806416
doi:
Types de publication
Journal Article
Langues
eng
Pagination
5154-5157Subventions
Organisme : Wenner-Gren Foundation
ID : FT2018-0002
Informations de copyright
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.