Extra-uterine low grade endometrioid stromal sarcoma arising from ovarian endometriosis: a case report and review of the literature.

Endometrioid stromal sarcoma Endometriosis Ovary Uterus

Journal

Gynecologic oncology research and practice
ISSN: 2053-6844
Titre abrégé: Gynecol Oncol Res Pract
Pays: England
ID NLM: 101676223

Informations de publication

Date de publication:
2019
Historique:
received: 19 11 2018
accepted: 16 01 2019
entrez: 7 2 2019
pubmed: 7 2 2019
medline: 7 2 2019
Statut: epublish

Résumé

Endometrial stromal sarcoma (ESS) is a rare neoplasm accounting for only 0.2% of female genital tract tumors. The primary extra-uterine location of ESS is an extremely uncommon occurrence. We present a case of a 64-year-old woman presenting with abdominopelvic and bilateral ovarian tumors with misleading clinical presentation and diagnostic challenge. The histopathological examination of the resected specimens disclosed the diagnosis of primary extra-uterine ESS arising from ovarian endometriosis. Adjuvant therapy with an aromatase inhibitor drug was prescribed for the patient, and she is still alive with no evidence of disease 7 months after surgery. The awareness of the potential extra-uterine location of ESS should lead to correct diagnosis as this tumor has histopathological features and clinical behavior similar to its uterine counterpart.

Sections du résumé

BACKGROUND BACKGROUND
Endometrial stromal sarcoma (ESS) is a rare neoplasm accounting for only 0.2% of female genital tract tumors. The primary extra-uterine location of ESS is an extremely uncommon occurrence.
CASE PRESENTATION METHODS
We present a case of a 64-year-old woman presenting with abdominopelvic and bilateral ovarian tumors with misleading clinical presentation and diagnostic challenge. The histopathological examination of the resected specimens disclosed the diagnosis of primary extra-uterine ESS arising from ovarian endometriosis. Adjuvant therapy with an aromatase inhibitor drug was prescribed for the patient, and she is still alive with no evidence of disease 7 months after surgery.
CONCLUSION CONCLUSIONS
The awareness of the potential extra-uterine location of ESS should lead to correct diagnosis as this tumor has histopathological features and clinical behavior similar to its uterine counterpart.

Identifiants

pubmed: 30723546
doi: 10.1186/s40661-019-0067-7
pii: 67
pmc: PMC6350347
doi:

Types de publication

Case Reports

Langues

eng

Pagination

2

Déclaration de conflit d'intérêts

Not applicable.Not applicable.All authors declare that they have no competing interest.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Références

Arch Pathol Lab Med. 2001 Aug;125(8):1088-90
pubmed: 11473465
Am J Obstet Gynecol. 1960 Sep;80:449-53
pubmed: 13798896
Acta Obstet Gynecol Scand. 1960;39:178-83
pubmed: 14410730
Obstet Gynecol. 2004 May;103(5 Pt 2):1051-4
pubmed: 15121605
J Obstet Gynaecol. 2004 Aug;24(5):596-7
pubmed: 15369960
J Gynecol Oncol. 2009 Jun;20(2):122-5
pubmed: 19590725
Hum Pathol. 2011 Jul;42(7):939-46
pubmed: 21316079
Gynecol Obstet Invest. 2012;74(4):288-97
pubmed: 22986788
Gynecol Oncol. 1990 Jan;36(1):147-51
pubmed: 2403959
Am J Surg Pathol. 2013 Nov;37(11):1635-47
pubmed: 24121169
Int J Clin Exp Pathol. 2013 Nov 15;6(12):2997-3002
pubmed: 24294390
Am J Surg Pathol. 2014 Mar;38(3):305-15
pubmed: 24525500
Ann Diagn Pathol. 2014 Jun;18(3):187-90
pubmed: 24636963
Semin Diagn Pathol. 2014 May;31(3):216-22
pubmed: 24863031
Histopathology. 2015 Jul;67(1):1-19
pubmed: 25355621
Ann Coloproctol. 2015 Apr;31(2):68-73
pubmed: 25960975
Mod Pathol. 2016 Jan;29 Suppl 1:S92-103
pubmed: 26715176
Obstet Gynecol Sci. 2016 Jul;59(4):323-7
pubmed: 27462602
Diagn Pathol. 2017 May 2;12(1):36
pubmed: 28464838
Pathol Int. 2017 Jun;67(6):327-329
pubmed: 28508463
J Clin Diagn Res. 2017 Mar;11(3):ED05-ED07
pubmed: 28511399
Gynecol Oncol Rep. 2017 Aug 08;21:119-121
pubmed: 28831418
Oncotarget. 2017 Jun 28;8(38):63345-63352
pubmed: 28968994
Eur J Med Res. 2017 Dec 2;22(1):52
pubmed: 29197420
Cancer. 1969 Jun;23(6):1413-22
pubmed: 4306105
Obstet Gynecol. 1971 Jun;37(6):920-41
pubmed: 4378308
Obstet Gynecol. 1970 Nov;36(5):702-7
pubmed: 5474000
Gynecol Oncol. 1981 Aug;12(1):129-38
pubmed: 7274760
Pathol Int. 1998 Apr;48(4):297-302
pubmed: 9648159

Auteurs

Boubacar Efared (B)

1Department of pathology, Hassan II University Hospital, Fès, Morocco.
Department of pathology, FSS, UAM, Niamey, Niger.

Ibrahim S Sidibé (IS)

1Department of pathology, Hassan II University Hospital, Fès, Morocco.

Fatimazahra Erregad (F)

1Department of pathology, Hassan II University Hospital, Fès, Morocco.

Nawal Hammas (N)

1Department of pathology, Hassan II University Hospital, Fès, Morocco.
3Laboratory of Biomedical and Translational Research, Faculty of Medicine and Pharmacology, Sidi Mohamed Ben Abdellah University, Fès, Morocco.

Laila Chbani (L)

1Department of pathology, Hassan II University Hospital, Fès, Morocco.
3Laboratory of Biomedical and Translational Research, Faculty of Medicine and Pharmacology, Sidi Mohamed Ben Abdellah University, Fès, Morocco.

Hinde El Fatemi (H)

1Department of pathology, Hassan II University Hospital, Fès, Morocco.
3Laboratory of Biomedical and Translational Research, Faculty of Medicine and Pharmacology, Sidi Mohamed Ben Abdellah University, Fès, Morocco.

Classifications MeSH