Review: Bioengineering approach for the repair and regeneration of peripheral nerve.

Composite materials Electrical stimulation Growth factor Peripheral nerve regeneration

Journal

Bioactive materials
ISSN: 2452-199X
Titre abrégé: Bioact Mater
Pays: China
ID NLM: 101685294

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 20 06 2018
revised: 03 09 2018
accepted: 03 09 2018
entrez: 7 2 2019
pubmed: 7 2 2019
medline: 7 2 2019
Statut: epublish

Résumé

Complex craniofacial surgeries of damaged tissues have several limitations, which present complications and challenges when trying to replicate facial function and structure. Traditional treatment techniques have shown suitable nerve function regeneration with various drawbacks. As technology continues to advance, new methods have been explored in order to regenerate damaged nerves in an effort to more efficiently and effectively regain original function and structure. This article will summarize recent bioengineering strategies involving biodegradable composite scaffolds, bioactive factors, and external stimuli alone or in combination to support peripheral nerve regeneration. Particular emphasis is made on the contributions of growth factors and electrical stimulation on the regenerative process.

Identifiants

pubmed: 30723843
doi: 10.1016/j.bioactmat.2018.09.001
pii: S2452-199X(18)30045-8
pmc: PMC6351356
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

107-113

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB020640
Pays : United States

Commentaires et corrections

Type : ErratumIn

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Auteurs

Joshua Moskow (J)

Department of Orthopaedic Surgery, University of Connecticut Health, 263Farmington Ave., Farmington, CT 06030, USA.
Department of Biomedical Engineering, University of Connecticut, 260Glenbrook Road, Unit 3247, Storrs, CT 06269, USA.

Bryan Ferrigno (B)

Department of Orthopaedic Surgery, University of Connecticut Health, 263Farmington Ave., Farmington, CT 06030, USA.

Nikhil Mistry (N)

Department of Orthopaedic Surgery, University of Connecticut Health, 263Farmington Ave., Farmington, CT 06030, USA.

Devina Jaiswal (D)

Department of Orthopaedic Surgery, University of Connecticut Health, 263Farmington Ave., Farmington, CT 06030, USA.
Department of Biomedical Engineering, University of Connecticut, 260Glenbrook Road, Unit 3247, Storrs, CT 06269, USA.

Ketan Bulsara (K)

Department of Surgery, University of Connecticut Health, 263 Farmington Ave., Farmington, CT 06030, USA.

Swetha Rudraiah (S)

Department of Orthopaedic Surgery, University of Connecticut Health, 263Farmington Ave., Farmington, CT 06030, USA.
Department of Pharmaceutical Sciences, School of Pharmacy, University of Saint Joseph, 229 Trumbull St., Hartford CT 06103, USA.

Sangamesh G Kumbar (SG)

Department of Orthopaedic Surgery, University of Connecticut Health, 263Farmington Ave., Farmington, CT 06030, USA.
Department of Biomedical Engineering, University of Connecticut, 260Glenbrook Road, Unit 3247, Storrs, CT 06269, USA.

Classifications MeSH