Exosomes endometrium prolactin prostasomes receptivity

Journal

Journal of extracellular vesicles
ISSN: 2001-3078
Titre abrégé: J Extracell Vesicles
Pays: United States
ID NLM: 101610479

Informations de publication

Date de publication:
2019
Historique:
received: 06 12 2017
revised: 26 11 2018
accepted: 21 12 2018
entrez: 8 2 2019
pubmed: 8 2 2019
medline: 8 2 2019
Statut: epublish

Résumé

Extracellular vesicles are highly abundant in seminal fluids and have a known role enhancing sperm function. Clinical pregnancy rates after IVF treatment are improved after female exposure to seminal fluid. Seminal fluid extracellular vesicles (SF-EVs) are candidate enhancers, however, whether SF-EVs interact with cells from the endometrium and modulate the implantation processes is unknown. Here, we investigated whether SF-EVs interact with endometrial stromal cells (ESCs) and enhance decidualisation, a requisite for implantation. SF-EVs, isolated from human seminal fluid (

Identifiants

pubmed: 30728921
doi: 10.1080/20013078.2019.1565262
pii: 1565262
pmc: PMC6352950
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1565262

Subventions

Organisme : NCRR NIH HHS
ID : P20 RR021905
Pays : United States
Organisme : NIGMS NIH HHS
ID : P30 GM118228
Pays : United States

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Auteurs

Helena Rodriguez-Caro (H)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.

Rebecca Dragovic (R)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.

Mengni Shen (M)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.

Eszter Dombi (E)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.

Ginny Mounce (G)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.

Kate Field (K)

Oxford Fertility, Institute of Reproductive Sciences, Oxford, UK.

Jamie Meadows (J)

Oxford Fertility, Institute of Reproductive Sciences, Oxford, UK.

Karen Turner (K)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.
Oxford Fertility, Institute of Reproductive Sciences, Oxford, UK.

Daniel Lunn (D)

Department of Statistics, University of Oxford, Oxford, UK.

Tim Child (T)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.
Oxford Fertility, Institute of Reproductive Sciences, Oxford, UK.

Jennifer Helen Southcombe (JH)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.

Ingrid Granne (I)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, Oxford, UK.

Classifications MeSH