A pilot study of the effects of Mycoplasma ovipneumoniae exposure on domestic lamb growth and performance.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2019
Historique:
received: 25 10 2018
accepted: 19 01 2019
entrez: 8 2 2019
pubmed: 8 2 2019
medline: 30 10 2019
Statut: epublish

Résumé

Mycoplasma ovipneumoniae is a globally distributed pathogen that has been associated with pneumonia in both domestic and wild Caprinae. It is closely related to M. hyopneumoniae, a respiratory pathogen of swine that is associated with decreased growth rates of pigs as well as clinical respiratory disease. In order to assess the effects of M. ovipneumoniae on lamb performance, we generated a cohort of lambs free of M. ovipneumoniae by segregation of test negative ewes after lambing, then compared the growth and carcass quality traits of M. ovipneumoniae-free and -colonized lambs from weaning to harvest. Some signs of respiratory disease were observed during the feeding trial in both lamb groups, but the M. ovipneumoniae-exposed group included more affected lambs and higher average disease scores. At harvest, lungs of lambs in both groups showed few grossly visible lesions, although the M. ovipneumoniae-exposed group did exhibit increased microscopic lung lesions (P<0.05). In addition, M. ovipneumoniae exposed lambs produced lower average daily gains (P<0.05), and lower yield grade carcasses (P<0.05) compared to those of non-exposed lambs. The results demonstrated the feasibility of test and segregation for elimination of M. ovipneumoniae from groups of sheep and suggested that this pathogen may impair lamb growth and productivity even in the absence of overt respiratory disease.

Identifiants

pubmed: 30730893
doi: 10.1371/journal.pone.0207420
pii: PONE-D-18-30886
pmc: PMC6366759
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0207420

Déclaration de conflit d'intérêts

I have read the journal's policy and the authors of this manuscript have the following competing interests. This specific study was supported by funding competitively awarded by the Wild Sheep Foundation. Additional research funding for the authors' respiratory disease related research has been received from the WSU Rocky Crate Endowment for Wild Sheep Disease Research, the US Department of Agriculture (including the Animal Plant Health Inspection Service and the US Forest Service), the US Geologic Survey, numerous chapters and affiliates of the Wild Sheep Foundation, and the WSU Fowler Emerging Infectious Diseases endowment. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

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Auteurs

Thomas E Besser (TE)

Department of Veterinary Microbiology and Pathology, Washington State University College of Veterinary Medicine, Pullman WA, United States of America.

Jessica Levy (J)

Department of Veterinary Microbiology and Pathology, Washington State University College of Veterinary Medicine, Pullman WA, United States of America.

Melissa Ackerman (M)

Department of Veterinary Clinical Sciences, Washington State University College of Veterinary Medicine, Pullman WA, United States of America.

Danielle Nelson (D)

Department of Veterinary Microbiology and Pathology, Washington State University College of Veterinary Medicine, Pullman WA, United States of America.

Kezia Manlove (K)

Department of Wildland Resources, Utah State University College of Natural Resources, Logan UT, United States of America.

Kathleen A Potter (KA)

Department of Veterinary Microbiology and Pathology, Washington State University College of Veterinary Medicine, Pullman WA, United States of America.

Jan Busboom (J)

Department of Animal Sciences, Washington State University College of Agricultural, Human, and Natural Resource Sciences, Pullman WA, United States of America.

Margaret Benson (M)

Department of Animal Sciences, Washington State University College of Agricultural, Human, and Natural Resource Sciences, Pullman WA, United States of America.

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Classifications MeSH