Psychosocial outcome and resilience after paediatric liver transplantation in young adults.
Activities of Daily Living
Adolescent
Adult
Age Factors
Anxiety
/ epidemiology
Child
Female
Follow-Up Studies
Health Status
Health Surveys
/ statistics & numerical data
Humans
Immunocompromised Host
Liver Transplantation
/ psychology
Male
Resilience, Psychological
Retrospective Studies
Self Concept
Transition to Adult Care
/ statistics & numerical data
Young Adult
Adherence
Liver transplantation
Paediatric
Psychosocial outcome
Quality of life
Transition
Journal
Clinics and research in hepatology and gastroenterology
ISSN: 2210-741X
Titre abrégé: Clin Res Hepatol Gastroenterol
Pays: France
ID NLM: 101553659
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
05
03
2018
revised:
15
08
2018
accepted:
27
08
2018
pubmed:
10
2
2019
medline:
31
3
2020
entrez:
10
2
2019
Statut:
ppublish
Résumé
The long-term psychosocial outcome of young adults after paediatric liver transplantation (LT) was investigated with the focus on day-to-day living. We aimed to capture patients' subjective perceptions of well-being and autonomy based on key physical outcome parameters. All patients following paediatric LT at Hannover Medical School born before 2002 with a post-transplant follow-up of at least four years were included in this study. This retrospective observational study compared psychosocial parameters obtained from a self-designed 77-item questionnaire with standard clinical outcome variables. Eighty-two patients (male: 57%) aged 13-41 years were included in the survey within a three-month period (response rate: 41%). With an adherence rate of 33%, all but two patients were immunosuppressed. In total, 53 patients had transitioned to adult care largely without problems. Eighty-three percent (n = 68) evaluated their current health status as "(very) good". Sixty-seven patients (82%) did not experience health-related anxiety in daily life. Our results demonstrate psychological stability and high self-esteem of young patients, as well as good integration into society and a high degree of normality during daily life after LT. Adherence rates are lower than anticipated and do not correlate with patients' understanding of their medical condition.
Sections du résumé
BACKGROUND AND OBJECTIVE
The long-term psychosocial outcome of young adults after paediatric liver transplantation (LT) was investigated with the focus on day-to-day living. We aimed to capture patients' subjective perceptions of well-being and autonomy based on key physical outcome parameters.
METHODS
All patients following paediatric LT at Hannover Medical School born before 2002 with a post-transplant follow-up of at least four years were included in this study. This retrospective observational study compared psychosocial parameters obtained from a self-designed 77-item questionnaire with standard clinical outcome variables.
RESULTS
Eighty-two patients (male: 57%) aged 13-41 years were included in the survey within a three-month period (response rate: 41%). With an adherence rate of 33%, all but two patients were immunosuppressed. In total, 53 patients had transitioned to adult care largely without problems. Eighty-three percent (n = 68) evaluated their current health status as "(very) good". Sixty-seven patients (82%) did not experience health-related anxiety in daily life.
CONCLUSIONS
Our results demonstrate psychological stability and high self-esteem of young patients, as well as good integration into society and a high degree of normality during daily life after LT. Adherence rates are lower than anticipated and do not correlate with patients' understanding of their medical condition.
Identifiants
pubmed: 30737022
pii: S2210-7401(18)30181-5
doi: 10.1016/j.clinre.2018.08.017
pii:
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
155-160Informations de copyright
Copyright © 2018. Published by Elsevier Masson SAS.