Postoperative radiation performed at the same surgical facility associated with improved overall survival in oral cavity squamous cell carcinoma.
Adolescent
Adult
Aged
Aged, 80 and over
Cancer Care Facilities
/ statistics & numerical data
Carcinoma, Squamous Cell
/ mortality
Chemotherapy, Adjuvant
Databases, Factual
Female
Humans
Male
Middle Aged
Mouth Neoplasms
/ mortality
Multivariate Analysis
Radiotherapy, Adjuvant
United States
/ epidemiology
Young Adult
National Cancer Database (NCDB)
facility location
oral cavity cancer
outcomes
postoperative radiation therapy (PORT)
Journal
Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
27
02
2018
revised:
10
12
2018
accepted:
24
01
2019
pubmed:
10
2
2019
medline:
18
11
2020
entrez:
10
2
2019
Statut:
ppublish
Résumé
The purpose of this analysis is to evaluate whether postoperative radiotherapy (PORT) at the same facility as surgery portends to better survival outcomes compared to PORT given at a different facility. Patients underwent upfront surgery at the National Cancer Database reporting facility followed by PORT. PORT was coded as performed at either the same facility or at a different facility as surgery. A total of 10 832 patients were selected. Five-year overall survival (OS) was higher in patients undergoing PORT at the same facility: 52.5% vs 48.4% (P < 0.001). PORT performed at the same facility was associated with improved OS under multivariate (HR, 0.92; P = 0.01) and propensity score matched (hazard ratio, 0.90; P = 0.004) analyses. OS was better among patients with head and neck cancer who received PORT at the same facility as surgery.
Sections du résumé
BACKGROUND
The purpose of this analysis is to evaluate whether postoperative radiotherapy (PORT) at the same facility as surgery portends to better survival outcomes compared to PORT given at a different facility.
METHODS
Patients underwent upfront surgery at the National Cancer Database reporting facility followed by PORT. PORT was coded as performed at either the same facility or at a different facility as surgery.
RESULTS
A total of 10 832 patients were selected. Five-year overall survival (OS) was higher in patients undergoing PORT at the same facility: 52.5% vs 48.4% (P < 0.001). PORT performed at the same facility was associated with improved OS under multivariate (HR, 0.92; P = 0.01) and propensity score matched (hazard ratio, 0.90; P = 0.004) analyses.
CONCLUSIONS
OS was better among patients with head and neck cancer who received PORT at the same facility as surgery.
Identifiants
pubmed: 30737961
doi: 10.1002/hed.25697
pmc: PMC6886367
mid: NIHMS1036939
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2299-2308Subventions
Organisme : NCI NIH HHS
ID : K12 CA086913
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA046934
Pays : United States
Informations de copyright
© 2019 Wiley Periodicals, Inc.
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