Feasibility of Cardiac Magnetic Resonance Wideband Protocol in Patients With Implantable Cardioverter Defibrillators and Its Utility for Defining Scar.


Journal

The American journal of cardiology
ISSN: 1879-1913
Titre abrégé: Am J Cardiol
Pays: United States
ID NLM: 0207277

Informations de publication

Date de publication:
15 04 2019
Historique:
received: 19 11 2018
revised: 10 01 2019
accepted: 11 01 2019
pubmed: 12 2 2019
medline: 9 1 2020
entrez: 12 2 2019
Statut: ppublish

Résumé

Implantable cardioverter defibrillators (ICDs) have been a relative contraindication to cardiovascular magnetic resonance imaging. Although cardiovascular magnetic resonance provides valuable information regarding scar in patients with ventricular arrhythmias or cardiomyopathy, ICDs in these patients frequently cause artifacts hindering accurate interpretation of both cine and late gadolinium enhancement (LGE) images. We sought to quantify the frequency and severity of artifact on LGE images and assess whether a modified wideband LGE protocol could improve the diagnostic yield of scar identification in agreement with invasive electroanatomic mapping (EAM). Forty-nine patients with ICDs and ventricular tachycardia (VT) or cardiomyopathy underwent CMR (Philips 1.5T), including standard and wideband LGE imaging. A safety algorithm was followed throughout the protocol. Standard and wideband LGE short-axis images were graded using an artifact score on a per-slice basis. LGE on wideband images was compared with EAM in 27 of 49 patients who underwent VT ablation. There were no adverse patient- or device-related events. With standard LGE imaging, 84% of patients demonstrated some degree of hyperenhancement artifact, which persisted in 22% on wideband LGE but with much less extent. Wideband LGE imaging resulted in an increase from 48% to 94% diagnostic-quality slices, with a significant reduction in artifact score, and correlated with EAM in 21 of 27 patients (78%). In conclusion, assessment of standard LGE is markedly limited by artifact in patients with ICD. The use of wideband LGE significantly improves image quality and can accurately localize myocardial scar before VT ablation.

Identifiants

pubmed: 30739658
pii: S0002-9149(19)30110-9
doi: 10.1016/j.amjcard.2019.01.018
pmc: PMC8240651
mid: NIHMS1711969
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1329-1335

Subventions

Organisme : NHLBI NIH HHS
ID : T32 HL007381
Pays : United States

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

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Auteurs

Amita Singh (A)

University of Chicago Medical Center, Chicago, Illinois.

Keigo Kawaji (K)

University of Chicago Medical Center, Chicago, Illinois.

Neha Goyal (N)

University of Chicago Medical Center, Chicago, Illinois.

Noreen T Nazir (NT)

University of Chicago Medical Center, Chicago, Illinois.

Andrew Beaser (A)

University of Chicago Medical Center, Chicago, Illinois.

Virginia O'Keefe-Baker (V)

University of Chicago Medical Center, Chicago, Illinois.

Karima Addetia (K)

University of Chicago Medical Center, Chicago, Illinois.

Roderick Tung (R)

University of Chicago Medical Center, Chicago, Illinois.

Peng Hu (P)

University of California, Los Angeles, California.

Victor Mor-Avi (V)

University of Chicago Medical Center, Chicago, Illinois.

Amit R Patel (AR)

University of Chicago Medical Center, Chicago, Illinois. Electronic address: apatel2@medicine.bsd.uchicago.edu.

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Classifications MeSH