Stepwise approach towards adoption of allergen immunotherapy for allergic rhinitis and asthma patients in daily practice in Belgium: a BelSACI-Abeforcal-EUFOREA statement.

Allergen-specific immunotherapy Allergic rhinitis Asthma Belgium

Journal

Clinical and translational allergy
ISSN: 2045-7022
Titre abrégé: Clin Transl Allergy
Pays: England
ID NLM: 101576043

Informations de publication

Date de publication:
2019
Historique:
received: 19 10 2018
accepted: 04 01 2019
entrez: 12 2 2019
pubmed: 12 2 2019
medline: 12 2 2019
Statut: epublish

Résumé

Allergic rhinitis (AR) affects 23-30% of the European population with equal prevalence reported in Belgium. Despite guidelines on the correct use of effective treatment, up to 40% of AR patients remain uncontrolled. Allergen immunotherapy (AIT) has been shown to improve the level of control up to 84% of patients being controlled by AIT. Recently, new guidelines for AIT have been published, supporting the clinical evidence for effectiveness of various subcutaneous and sublingual products for AIT in patients who are allergic to airborne allergens. AIT in AR patients not only reduces nasal and/or ocular symptoms but also induces tolerance and has preventive potential. Adoption of AIT into daily clinical practice in Belgium and other European countries is hampered primarily by reimbursement issues of each of the single products but also by several patient- and physician-related factors. Patients need to be better informed about the effectiveness of AIT and the different routes of administration of AIT. Physicians dealing with AR patients should inform patients on tolerance-inducing effects of AIT and are in the need of a harmonized and practical guide that supports them in selecting eligible patients for AIT, in choosing evidence-based AIT products and in following treatment protocols with proven efficacy. Therefore, a stepwise and holistic approach is needed for better adoption of AIT in the real-life setting in Belgium.

Identifiants

pubmed: 30740211
doi: 10.1186/s13601-019-0243-1
pii: 243
pmc: PMC6360767
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1

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Auteurs

P W Hellings (PW)

1ENT Clinical Department, University Hospital Leuven, Kapucijnenvoer 33, 3000 Louvain, Belgium.
2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.

B Pugin (B)

2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
European Forum for Research and Education in Allergy and Airway Diseases, Brussels, Belgium.

G Mariën (G)

European Forum for Research and Education in Allergy and Airway Diseases, Brussels, Belgium.

C Bachert (C)

4ENT Clinical Department, University Hospital Ghent, Ghent, Belgium.
5Upper Airways Research Laboratory, University of Ghent, Ghent, Belgium.

C Breynaert (C)

2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
6Internal Medicine Clinical Department, UZ Leuven, Louvain, Belgium.

D M Bullens (DM)

7Pediatrics Clinical Department, UZ Leuven, Louvain, Belgium.

J L Ceuppens (JL)

2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
6Internal Medicine Clinical Department, UZ Leuven, Louvain, Belgium.

G Clement (G)

8ENT Clinical Department, AZ Damiaan, Ostend, Belgium.

T Cox (T)

9ENT Clinical Department, Jessa Hospital, Hasselt, Belgium.

D Ebo (D)

10Immunology-Allergology-Rheumatology, University Hospital Antwerp, Antwerp, Belgium.

P Gevaert (P)

4ENT Clinical Department, University Hospital Ghent, Ghent, Belgium.
5Upper Airways Research Laboratory, University of Ghent, Ghent, Belgium.

S Halewyck (S)

11ENT Clinical Department, UZ Brussel, Brussels, Belgium.
ENT Clinical Department, ASZ Aalst, Aalst, Belgium.

V Hox (V)

13ENT Clinical Department, Clinique Universitaires Saint-Luc, Brussels, Belgium.

K Ladha (K)

14Pediatrics Clinical Department, CHU Charleroi, Charleroi, Belgium.

R Jacobs (R)

15ENT Clinical Department, AZ Sint-Blasius, Dendermonde, Belgium.

P Rombaux (P)

13ENT Clinical Department, Clinique Universitaires Saint-Luc, Brussels, Belgium.

R Schrijvers (R)

2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
6Internal Medicine Clinical Department, UZ Leuven, Louvain, Belgium.

K Speleman (K)

16ENT Clinical Department, AZ Sint-Jan, Brugge, Belgium.

X Van der Brempt (X)

Allergopole, Clinique Saint-Luc Bouge, Namur, Belgium.

L Van Gerven (L)

1ENT Clinical Department, University Hospital Leuven, Kapucijnenvoer 33, 3000 Louvain, Belgium.

O Vanderveken (O)

18ENT Clinical Department, University Hospital Antwerp, Antwerp, Belgium.

B Verhaeghe (B)

ENT Clinical Department, St-Andries ziekenhuis, Tielt, Belgium.

K Vierstraete (K)

20ENT Clinical Department, AZ Groeninge, Kortrijk, Belgium.

S Vlaminck (S)

21ENT Clinical Department, AZ Delta Roeselare, Roeselare, Belgium.

J-B Watelet (JB)

4ENT Clinical Department, University Hospital Ghent, Ghent, Belgium.

J Bousquet (J)

22Department of Respiratory Disease, University Hospital Arnaud de Villeneuve, Montpellier, France.

S F Seys (SF)

1ENT Clinical Department, University Hospital Leuven, Kapucijnenvoer 33, 3000 Louvain, Belgium.
2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.

Classifications MeSH