Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study.
Allergy
Atopic dermatitis
Child
Paraben
Triclosan
Wheezing
Journal
Asia Pacific allergy
ISSN: 2233-8276
Titre abrégé: Asia Pac Allergy
Pays: Netherlands
ID NLM: 101561954
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
13
01
2018
accepted:
14
01
2018
entrez:
12
2
2019
pubmed:
12
2
2019
medline:
12
2
2019
Statut:
epublish
Résumé
Previous studies have reported that exposure to paraben (Pb) and triclosan (TCS) is associated with allergies. However, Pb and TCS exposure in the Japanese population is not fully understood. The present study was aimed to examine such exposure among Japanese individuals with allergic diseases. This cross-sectional study included the International Study of Asthma and Allergies in Childhood questionnaire survey to evaluate allergic outcomes and the collection of urine samples to examine Pb and TCS exposure. Pb containing daily commodities was used in 84.8% children. Pb use was positively associated with current atopic dermatitis (adjusted odds ratio, 4.61; 95% confidence interval, 1.23-17.3). Urinary Pb concentrations were increased significantly in those with current atopic dermatitis (AD) (median, 4.58 vs. 0; Urinary levels of Pb were associated with current AD in children. We should pay more attention about Pb and TCS.
Sections du résumé
BACKGROUND
BACKGROUND
Previous studies have reported that exposure to paraben (Pb) and triclosan (TCS) is associated with allergies. However, Pb and TCS exposure in the Japanese population is not fully understood.
OBJECTIVES
OBJECTIVE
The present study was aimed to examine such exposure among Japanese individuals with allergic diseases.
METHODS
METHODS
This cross-sectional study included the International Study of Asthma and Allergies in Childhood questionnaire survey to evaluate allergic outcomes and the collection of urine samples to examine Pb and TCS exposure.
RESULTS
RESULTS
Pb containing daily commodities was used in 84.8% children. Pb use was positively associated with current atopic dermatitis (adjusted odds ratio, 4.61; 95% confidence interval, 1.23-17.3). Urinary Pb concentrations were increased significantly in those with current atopic dermatitis (AD) (median, 4.58 vs. 0;
CONCLUSION
CONCLUSIONS
Urinary levels of Pb were associated with current AD in children. We should pay more attention about Pb and TCS.
Identifiants
pubmed: 30740353
doi: 10.5415/apallergy.2019.9.e5
pii: 2019090103
pmc: PMC6365653
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e5Commentaires et corrections
Type : ErratumIn
Déclaration de conflit d'intérêts
Conflict of Interest: The authors have no financial conflicts of interest.
Références
Thorax. 2000 Aug;55 Suppl 1:S2-10
pubmed: 10943631
Environ Health Perspect. 2006 Dec;114(12):1843-6
pubmed: 17185273
Environ Health Perspect. 2008 Mar;116(3):303-7
pubmed: 18335095
Environ Health Perspect. 2010 May;118(5):679-85
pubmed: 20056562
JAMA. 2011 Apr 13;305(14):1400-1
pubmed: 21486968
J Allergy Clin Immunol. 2012 Aug;130(2):453-60.e7
pubmed: 22704536
Allergy. 2013 Jan;68(1):84-91
pubmed: 23146048
Environ Sci Technol. 2013 Dec 17;47(24):14442-9
pubmed: 24261694
World Allergy Organ J. 2014 May 19;7(1):12
pubmed: 24940476
J Allergy Clin Immunol. 2014 Oct;134(4):824-830.e6
pubmed: 25282564
Allergy Asthma Proc. 2014 Nov-Dec;35(6):475-81
pubmed: 25584915
Reprod Toxicol. 2015 Apr;52:93-100
pubmed: 25728410
Allergy. 2015 Jun;70(6):653-60
pubmed: 25753462
Int J Hyg Environ Health. 2016 May;219(3):311-6
pubmed: 26765087
Reprod Toxicol. 2016 Aug;63:107-13
pubmed: 27189314
Allergy. 2017 Nov;72(11):1768-1777
pubmed: 28281298
Curr Probl Pediatr Adolesc Health Care. 2017 May;47(5):107-118
pubmed: 28526231
Pediatr Allergy Immunol. 2017 Dec;28(8):746-753
pubmed: 28892561
Nat Immunol. 2017 Sep 19;18(10):1076-1083
pubmed: 28926539
J Allergy Clin Immunol. 2018 Jul;142(1):269-278.e15
pubmed: 29111213
Pediatr Allergy Immunol. 2018 Sep;29(6):657-660
pubmed: 29882265
J Allergy Clin Immunol. 2018 Sep 5;:null
pubmed: 30194988
Allergy. 2018 Oct 24;:null
pubmed: 30353933
Eur Respir J. 1995 Mar;8(3):483-91
pubmed: 7789502