Pymetrozine activates TRPV channels of brown planthopper Nilaparvata lugens.
Chordotonal organ
Inactive
Nanchung
Nilaparvata lugens
Pymetrozine
TRPV channel
Journal
Pesticide biochemistry and physiology
ISSN: 1095-9939
Titre abrégé: Pestic Biochem Physiol
Pays: United States
ID NLM: 1301573
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
22
09
2018
revised:
30
10
2018
accepted:
04
11
2018
entrez:
13
2
2019
pubmed:
13
2
2019
medline:
26
2
2019
Statut:
ppublish
Résumé
The commercial insecticide pymetrozine has been extensively used for brown planthopper control in East Asia. The transient receptor potential vanilloid (TRPV) channel, which consists of two proteins, Nanchung (Nan) and Inactive (Iav), has recently been shown to be the molecular target of pymetrozine in the fruit fly (Drosophila melanogaster) and pea aphid (Acyrthosiphon pisum). In this study, we characterized the Nan and Iav TRPV channel subunits of N. lugens and measured the action of pymetrozine on them. NlNan and NlIav are structurally similar to homologs from other insects. The expression pattern analysis of various body parts showed that NlNan and NlIav were both more abundantly expressed in antennae. When NlNan and NlIav were co-expressed in Xenopus laevis oocytes, they formed channels with high sensitivity to pymetrozine (EC
Identifiants
pubmed: 30744899
pii: S0048-3575(18)30453-X
doi: 10.1016/j.pestbp.2018.11.005
pii:
doi:
Substances chimiques
Insect Proteins
0
Insecticides
0
Transient Receptor Potential Channels
0
Triazines
0
pymetrozine
F0G3V7874J
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
77-86Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.