Obsessive-compulsive disorder comorbid with schizophrenia and bipolar disorder.
Antipsychotic-induced obsessive-compulsive symptoms
bipolar disorder
obsessive-compulsive disorder
obsessive-compulsive symptoms
schizo-obsessive disorder
schizophrenia
Journal
Indian journal of psychiatry
ISSN: 0019-5545
Titre abrégé: Indian J Psychiatry
Pays: India
ID NLM: 0013255
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
entrez:
13
2
2019
pubmed:
13
2
2019
medline:
13
2
2019
Statut:
ppublish
Résumé
Obsessive Compulsive Disorder (OCD) and Obsessive Compulsive Symptoms (OCS) are known to be highly comorbid with bipolar disorder and schizophrenia. Comorbid OCD/OCS influences the course of schizophrenia and bipolar disorder. There is also some evidence to suggest that a diagnosis of OCD may be associated with elevated risk for later development of psychosis and bipolar disorder. Comorbid OCD/OCS is associated with a greater severity of schizophrenia phenotype and poorer prognosis. In addition, certain atypical antipsychotics, clozapine in particular are known to induce or worsen OCS in schizophrenia. OCD when comorbid with bipolar disorder mostly runs an episodic course with worsening and improvement of OCD/OCS in depressive and in manic/hypomanic phases respectively. There is limited systematic data on the treatment of OCD in schizophrenia and bipolar disorder. When OCD presents in the context of schizophrenia, management may include treatment with atypical antipsychotics with limited serotonergic properties, changing the antipsychotic, reduction in the dose of the antipsychotic, addition of cognitive-behavior therapy (CBT), or a specific serotonin reuptake inhibitor (SSRI). When OCD is comorbid with bipolar disorder, mood stabilization is the priority. CBT may be preferred over SSRIs to treat OCD/OCS that persist in between the mood episodes because SSRIs may induce a switch or worsen the course of bipolar disorder. SSRIs when indicated have to be used judiciously under the cover of adequate mood stabilization.
Identifiants
pubmed: 30745688
doi: 10.4103/psychiatry.IndianJPsychiatry_527_18
pii: IJPsy-61-140
pmc: PMC6343407
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
S140-S148Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
CNS Drugs. 2004;18(14):989-1010
pubmed: 15584769
Eur Arch Psychiatry Clin Neurosci. 2005 Feb;255(1):65-71
pubmed: 15711895
Asian J Psychiatr. 2017 Oct;29:30-34
pubmed: 29061423
Can J Psychiatry. 2006 Oct;51(12):746-54
pubmed: 17168249
Bipolar Disord. 2007 Nov;9(7):722-9
pubmed: 17988362
Aust N Z J Psychiatry. 2011 May;45(5):400-6
pubmed: 21087087
Psychiatry Res. 2015 Mar 30;226(1):368-75
pubmed: 25681006
Eur Arch Psychiatry Clin Neurosci. 2006 Jun;256(4):240-5
pubmed: 16683062
Psychiatry Res. 2013 Nov 30;210(1):21-8
pubmed: 23810510
J Nerv Ment Dis. 2007 Sep;195(9):765-8
pubmed: 17984777
Schizophr Res. 2005 Jun 15;75(2-3):349-62
pubmed: 15885526
J Clin Psychopharmacol. 2008 Apr;28(2):214-8
pubmed: 18344733
Curr Pharm Des. 2010;16(5):502-15
pubmed: 19909228
Compr Psychiatry. 1998 Sep-Oct;39(5):308-11
pubmed: 9777284
Psychiatry Clin Neurosci. 2011 Aug;65(5):423-33
pubmed: 21851451
Int Clin Psychopharmacol. 2000 May;15(3):169-73
pubmed: 10870875
World J Psychiatry. 2016 Dec 22;6(4):449-455
pubmed: 28078209
Compr Psychiatry. 2015 Jan;56:141-8
pubmed: 25308405
Psychiatry Investig. 2016 May;13(3):370-1
pubmed: 27247606
Psychiatry Res. 2015 Aug 30;228(3):363-7
pubmed: 26144581
Prog Neuropsychopharmacol Biol Psychiatry. 2003 May;27(3):333-46
pubmed: 12691768
J Affect Disord. 2015 Nov 1;186:99-109
pubmed: 26233320
Clin Neuropharmacol. 2011 Nov-Dec;34(6):256-7
pubmed: 22104635
Eur Arch Psychiatry Clin Neurosci. 1998;248(5):240-4
pubmed: 9840370
Adv Med. 2014;2014:317980
pubmed: 26556409
Psychopathology. 2010;43(2):69-78
pubmed: 20068377
Iran J Psychiatry Behav Sci. 2016 Aug 17;10(3):e3604
pubmed: 27826323
Acta Psychiatr Scand. 2000 Jul;102(1):32-7
pubmed: 10892607
J Clin Psychiatry. 1998 Sep;59(9):465-71
pubmed: 9771817
J Psychiatr Res. 2006 Apr;40(3):189-91
pubmed: 15913654
Psychiatr Pol. 2001 Jan-Feb;35(1):47-57
pubmed: 11324381
Acta Psychiatr Scand. 2014 Sep;130(3):214-26
pubmed: 24571191
Compr Psychiatry. 1995 May-Jun;36(3):187-94
pubmed: 7648841
Braz J Psychiatry. 2005 Jun;27(2):139-42
pubmed: 15962140
Aust N Z J Psychiatry. 2012 Feb;46(2):161-9
pubmed: 22311532
Psychiatry Clin Neurosci. 1995 Aug;49(4):201-7
pubmed: 9179938
Psychiatry Res. 2009 Nov 30;170(1):52-60
pubmed: 19800695
Psychopharmacology (Berl). 2013 Nov;230(1):49-55
pubmed: 23660601
Int J Neuropsychopharmacol. 2015 May 04;18(9):
pubmed: 25939614
Schizophr Res. 2005 Jul 15;76(2-3):309-16
pubmed: 15949663
J Affect Disord. 1997 Oct;46(1):15-23
pubmed: 9387083
Compr Psychiatry. 2009 Sep-Oct;50(5):437-42
pubmed: 19683614
Ther Adv Psychopharmacol. 2011 Dec;1(6):181-8
pubmed: 23983945
Asian J Psychiatr. 2015 Jun;15:56-61
pubmed: 26013671
Am J Med Genet B Neuropsychiatr Genet. 2005 Feb 5;133B(1):31-6
pubmed: 15635656
Eur Psychiatry. 2002 Nov;17(7):407-10
pubmed: 12547307
J Clin Psychiatry. 2007 Apr;68(4):542-5
pubmed: 17474809
Front Hum Neurosci. 2014 Jul 29;8:560
pubmed: 25120459
Psychol Med. 2012 Jul;42(7):1449-59
pubmed: 22099954
Am J Psychiatry. 2004 Dec;161(12):2222-9
pubmed: 15569893
J Ment Sci. 1957 Oct;103(433):773-85
pubmed: 13481587
J Affect Disord. 2015 Mar 15;174:367-71
pubmed: 25545603
Early Interv Psychiatry. 2017 Dec;11(6):480-487
pubmed: 26456932
Shanghai Arch Psychiatry. 2015 Oct;27(5):307-10
pubmed: 26977128
Asian J Psychiatr. 2016 Apr;20:12-4
pubmed: 27025465
Compr Psychiatry. 2010 May-Jun;51(3):293-7
pubmed: 20399339
Psychiatr Clin North Am. 2009 Dec;32(4):835-51
pubmed: 19944887
Eur Neuropsychopharmacol. 2014 Sep;24(9):1454-62
pubmed: 25048540
Int Clin Psychopharmacol. 2013 Mar;28(2):96-8
pubmed: 23211492
Biol Psychiatry. 2006 Aug 1;60(3):207-17
pubmed: 16875929
Compr Psychiatry. 2012 Jul;53(5):480-3
pubmed: 22036006
Eur Psychiatry. 2014 Mar;29(3):160-6
pubmed: 23764406
Psychiatry Res. 2000 Aug 28;99(2):83-91
pubmed: 10963984
Acta Neuropsychiatr. 2010 Apr;22(2):81-6
pubmed: 25385033
Am J Med Genet B Neuropsychiatr Genet. 2011 Dec;156B(8):949-59
pubmed: 21990008
Arch Gen Psychiatry. 2003 Dec;60(12):1187-92
pubmed: 14662550
Aust N Z J Psychiatry. 2014 Oct;48(10):957
pubmed: 24711576
Curr Neuropharmacol. 2012 Mar;10(1):88-95
pubmed: 22942882
Acta Psychiatr Scand. 2014 May;129(5):343-58
pubmed: 24506190
Psychiatry Res. 1995 Nov 29;59(1-2):57-64
pubmed: 8771221
Schizophr Res. 2014 Feb;152(2-3):458-68
pubmed: 24361303
Am J Psychiatry. 2009 Mar;166(3):329-36
pubmed: 19188283
Psychol Med. 2011 Nov;41(11):2361-73
pubmed: 21466748
Am J Psychiatry. 2007 Jul;164(7 Suppl):5-53
pubmed: 17849776
Eur Arch Psychiatry Clin Neurosci. 2006 Oct;256(7):428-36
pubmed: 16783496
Depress Anxiety. 2012 Mar;29(3):226-33
pubmed: 22109969
JAMA Psychiatry. 2014 Nov;71(11):1215-21
pubmed: 25188738
Psychiatry Res. 2018 Mar;261:332-337
pubmed: 29334657
Compr Psychiatry. 2008 May-Jun;49(3):262-8
pubmed: 18396185
J Clin Psychiatry. 2002 Dec;63(12):1129-34
pubmed: 12523872
Psychol Med. 2010 Jun;40(6):921-33
pubmed: 19818202
Int J Psychiatry Clin Pract. 2017 Mar;21(1):70-74
pubmed: 27646489
Acta Psychiatr Scand. 2011 Feb;123(2):136-46
pubmed: 20880068
Encephale. 2002 Jan-Feb;28(1):21-8
pubmed: 11963340
Prog Neuropsychopharmacol Biol Psychiatry. 2009 Aug 31;33(6):1009-12
pubmed: 19447155
Expert Rev Neurother. 2009 Jan;9(1):99-107
pubmed: 19102672
Psychiatry Res. 2008 Oct 30;161(1):105-8
pubmed: 18718674
J Psychiatry Neurosci. 2015 Mar;40(2):89-99
pubmed: 25268790
Compr Psychiatry. 2000 Jul-Aug;41(4):242-7
pubmed: 10929790
Psychiatry Res. 2011 Jun 30;188(1):34-9
pubmed: 21131056
Schizophr Bull. 2011 Jul;37(4):811-21
pubmed: 19959704
J Affect Disord. 2006 Dec;96(3):249-58
pubmed: 16904187
Psychiatry Res. 2016 Dec 30;246:119-128
pubmed: 27690134
Am J Psychiatry. 1986 Apr;143(4):437-41
pubmed: 3953886
Schizophr Bull. 2013 Jan;39(1):151-60
pubmed: 21799212
Curr Psychiatry Rep. 2014 Nov;16(11):510
pubmed: 25256097
Psychiatry Res. 2016 Jul 30;241:221-3
pubmed: 27183107
Schizophr Bull. 2015 Sep;41(5):1076-83
pubmed: 25512596
Compr Psychiatry. 2007 May-Jun;48(3):245-51
pubmed: 17445518
Clin Neuropharmacol. 2009 Jul-Aug;32(4):227-9
pubmed: 19644230
Int Clin Psychopharmacol. 1999 Mar;14(2):95-100
pubmed: 10220124
J Psychopharmacol. 2013 Apr;27(4):349-57
pubmed: 23095245
J Psychopharmacol. 2009 Jan;23(1):6-13
pubmed: 18515449
Eur Arch Psychiatry Clin Neurosci. 2014 Nov;264 Suppl 1:S67-82
pubmed: 25214389
Pharmacopsychiatry. 2014 May;47(3):118-20
pubmed: 24846087