DIAGNOSTIC ACCURACY OF THE LEVER SIGN IN DETECTING ANTERIOR CRUCIATE LIGAMENT TEARS: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Anterior cruciate ligament Lelli test Lever sign test diagnostic accuracy knee movement system

Journal

International journal of sports physical therapy
ISSN: 2159-2896
Titre abrégé: Int J Sports Phys Ther
Pays: United States
ID NLM: 101553140

Informations de publication

Date de publication:
Feb 2019
Historique:
entrez: 13 2 2019
pubmed: 13 2 2019
medline: 13 2 2019
Statut: ppublish

Résumé

The anterior cruciate ligament (ACL) is one of the most commonly injured ligaments in the knee. With the prevalence of ACL tears increasing, there is a growing need for clinical tests to rule in and rule out a suspected tear. A new clinical test for detecting ACL tears has been introduced with preliminary studies showing promising results. To systematically review and analyze information from the current literature on the diagnostic accuracy of the Lever Sign test for the use of diagnosing anterior cruciate ligament (ACL) injuries in a clinical setting. Systematic review and meta-analysis. A computerized search of PubMed, Cinahl, Scopus, and Proquest databases as well as a hand-search was completed on all available literature using keywords relating to the diagnostic accuracy of the Lever Sign Test. A quality assessment was performed on each article included in this review utilizing the Quality Assessment of Diagnostic Accuracy Studies (QUADAS). Eight articles were included, with only three studies exhibiting high quality, however the study samples were heterogenous. Included studies indicated that the Lever Sign test is both sensitive and specific in diagnosing ACL tears. Pooled sensitivity and specificity were 0.77 and 0.90, respectively. The negative likelihood ratio is 0.22 and the positive likelihood ratio is 6.60. The Lever Sign test is comparable to other clinical tests used in current practice to detect an ACL rupture. The pooled data from current available literature on the Lever Sign indicate that a positive or negative test should result in a moderate shift in post-test probability. This test may be used in addition to other tests to rule in and rule out the presence of an ACL rupture. 2a- Systematic Review of Level 2 diagnostic studies.

Sections du résumé

BACKGROUND BACKGROUND
The anterior cruciate ligament (ACL) is one of the most commonly injured ligaments in the knee. With the prevalence of ACL tears increasing, there is a growing need for clinical tests to rule in and rule out a suspected tear. A new clinical test for detecting ACL tears has been introduced with preliminary studies showing promising results.
HYPOTHESIS/PURPOSE OBJECTIVE
To systematically review and analyze information from the current literature on the diagnostic accuracy of the Lever Sign test for the use of diagnosing anterior cruciate ligament (ACL) injuries in a clinical setting.
STUDY DESIGN METHODS
Systematic review and meta-analysis.
METHODS METHODS
A computerized search of PubMed, Cinahl, Scopus, and Proquest databases as well as a hand-search was completed on all available literature using keywords relating to the diagnostic accuracy of the Lever Sign Test. A quality assessment was performed on each article included in this review utilizing the Quality Assessment of Diagnostic Accuracy Studies (QUADAS).
RESULTS RESULTS
Eight articles were included, with only three studies exhibiting high quality, however the study samples were heterogenous. Included studies indicated that the Lever Sign test is both sensitive and specific in diagnosing ACL tears. Pooled sensitivity and specificity were 0.77 and 0.90, respectively. The negative likelihood ratio is 0.22 and the positive likelihood ratio is 6.60.
CONCLUSION CONCLUSIONS
The Lever Sign test is comparable to other clinical tests used in current practice to detect an ACL rupture. The pooled data from current available literature on the Lever Sign indicate that a positive or negative test should result in a moderate shift in post-test probability. This test may be used in addition to other tests to rule in and rule out the presence of an ACL rupture.
LEVEL OF EVIDENCE METHODS
2a- Systematic Review of Level 2 diagnostic studies.

Identifiants

pubmed: 30746288
pmc: PMC6350660

Types de publication

Journal Article

Langues

eng

Pagination

2-13

Références

BMC Med Res Methodol. 2003 Nov 10;3:25
pubmed: 14606960
Arthroscopy. 2004 Sep;20(7):696-700
pubmed: 15346110
Acad Radiol. 2006 Jul;13(7):803-10
pubmed: 16777553
Br J Sports Med. 2008 Feb;42(2):80-92; discussion 92
pubmed: 17720798
J Orthop Sports Phys Ther. 2007 Sep;37(9):541-50
pubmed: 17939613
Strategies Trauma Limb Reconstr. 2007 Apr;2(1):1-12
pubmed: 18427909
J Orthop Surg Res. 2008 May 19;3:19
pubmed: 18489779
Br J Sports Med. 2008 Jun;42(6):394-412
pubmed: 18539658
Ann Intern Med. 2009 Aug 18;151(4):264-9, W64
pubmed: 19622511
Man Ther. 2011 Feb;16(1):21-5
pubmed: 20685150
Res Sports Med. 2012 Jul;20(3-4):157-79
pubmed: 22742074
Knee Surg Sports Traumatol Arthrosc. 2013 Aug;21(8):1895-903
pubmed: 23085822
Am J Sports Med. 2014 Apr;42(4):959-64
pubmed: 24519183
Knee Surg Sports Traumatol Arthrosc. 2016 Sep;24(9):2794-7
pubmed: 25536951
Springerplus. 2015 Dec 30;4:830
pubmed: 26753117
Am J Sports Med. 1989 Jul-Aug;17(4):463-71
pubmed: 2782529
Arthroscopy. 2017 Aug;33(8):1560-1566
pubmed: 28499922
Curr Rev Musculoskelet Med. 2017 Sep;10(3):281-288
pubmed: 28656531
Iowa Orthop J. 2017;37:71-79
pubmed: 28852338
Orthop J Sports Med. 2017 Oct 11;5(10):2325967117729809
pubmed: 29051898
J Orthop Sports Phys Ther. 2017 Nov;47(11):A1-A47
pubmed: 29089004
Int J Sports Phys Ther. 2017 Dec;12(7):1057-1067
pubmed: 29234557
Orthop J Sports Med. 2018 Mar 16;6(3):2325967118759631
pubmed: 29568784
Biometrics. 1977 Mar;33(1):159-74
pubmed: 843571

Auteurs

Kristin Abruscato (K)

Department of Physical Therapy, Walsh University, North Canton, OH, USA.

Kelsie Browning (K)

Department of Physical Therapy, Walsh University, North Canton, OH, USA.

Daniel Deleandro (D)

Department of Physical Therapy, Walsh University, North Canton, OH, USA.

Quinn Menard (Q)

Department of Physical Therapy, Walsh University, North Canton, OH, USA.

Mark Wilhelm (M)

Department of Physical Therapy, Walsh University, North Canton, OH, USA.

Amy Hassen (A)

Department of Physical Therapy, Walsh University, North Canton, OH, USA.

Classifications MeSH