Oxidative Pathways of Deoxyribose and Deoxyribonate Catabolism.
deoxyribonate catabolism
deoxyribose catabolism
high-throughput genetics
Journal
mSystems
ISSN: 2379-5077
Titre abrégé: mSystems
Pays: United States
ID NLM: 101680636
Informations de publication
Date de publication:
Historique:
received:
19
11
2018
accepted:
12
01
2019
entrez:
13
2
2019
pubmed:
13
2
2019
medline:
13
2
2019
Statut:
epublish
Résumé
Using genome-wide mutant fitness assays in diverse bacteria, we identified novel oxidative pathways for the catabolism of 2-deoxy-d-ribose and 2-deoxy-d-ribonate. We propose that deoxyribose is oxidized to deoxyribonate, oxidized to ketodeoxyribonate, and cleaved to acetyl coenzyme A (acetyl-CoA) and glyceryl-CoA. We have genetic evidence for this pathway in three genera of bacteria, and we confirmed the oxidation of deoxyribose to ketodeoxyribonate
Identifiants
pubmed: 30746495
doi: 10.1128/mSystems.00297-18
pii: mSystems00297-18
pmc: PMC6365646
pii:
doi:
Banques de données
figshare
['10.6084/m9.figshare.7304159.v1']
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NIH HHS
ID : S10 OD018174
Pays : United States
Organisme : NIH HHS
ID : S10 OD020062
Pays : United States
Références
Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8884-9
pubmed: 10430865
J Bacteriol. 2000 Feb;182(4):869-73
pubmed: 10648508
Biochemistry. 1965 Jan;4:159-65
pubmed: 14285233
Appl Environ Microbiol. 2005 Aug;71(8):4339-44
pubmed: 16085822
Rapid Commun Mass Spectrom. 2006;20(13):1989-94
pubmed: 16755610
J Biol Chem. 2006 Nov 3;281(44):33521-36
pubmed: 16950779
FEBS Lett. 2008 Sep 3;582(20):3025-8
pubmed: 18675808
Nucleic Acids Res. 2010 Jan;38(Database issue):D396-400
pubmed: 19906701
Bioinformatics. 2010 Jul 1;26(13):1608-15
pubmed: 20472543
Proteomics. 2011 Feb;11(4):535-53
pubmed: 21243637
Methods Enzymol. 2011;498:349-61
pubmed: 21601685
ACS Chem Biol. 2013 Jan 18;8(1):189-99
pubmed: 23082955
Nucleic Acids Res. 2013 Jan;41(Database issue):D387-95
pubmed: 23197656
Mol Cell Proteomics. 2013 Mar;12(3):549-56
pubmed: 23250051
J Proteome Res. 2013 Jun 7;12(6):2323-39
pubmed: 23514362
Appl Microbiol Biotechnol. 2014 Jan;98(1):137-49
pubmed: 24136472
BMC Genomics. 2013 Nov 01;14:745
pubmed: 24175918
Nat Chem Biol. 2014 Jan;10(1):42-9
pubmed: 24240508
Nucleic Acids Res. 2014 Jan;42(Database issue):D222-30
pubmed: 24288371
Nucleic Acids Res. 2014 Jan;42(Database issue):D206-14
pubmed: 24293654
Nat Methods. 2014 Feb;11(2):167-70
pubmed: 24336358
J Proteomics. 2014 Sep 23;109:212-27
pubmed: 25026441
Appl Microbiol Biotechnol. 2014 Dec;98(23):9653-65
pubmed: 25236800
Biochemistry. 1989 Feb 7;28(3):1027-32
pubmed: 2523732
Nucleic Acids Res. 2015 Jan;43(Database issue):D222-6
pubmed: 25414356
MBio. 2015 Feb 03;6(1):null
pubmed: 25650399
PLoS One. 2015 Mar 30;10(3):e0122957
pubmed: 25823014
MBio. 2015 May 12;6(3):e00306-15
pubmed: 25968644
PLoS Biol. 2015 Jun 11;13(6):e1002168
pubmed: 26066900
Nucleic Acids Res. 2016 Jan 4;44(D1):D457-62
pubmed: 26476454
Biochem Soc Trans. 2016 Jun 15;44(3):961-71
pubmed: 27284066
Nucleic Acids Res. 2017 Jan 4;45(D1):D535-D542
pubmed: 27899627
mSystems. 2017 Aug 15;2(4):null
pubmed: 28845458
PLoS Biol. 2017 Sep 22;15(9):e2002860
pubmed: 28938018
Nat Microbiol. 2017 Dec;2(12):1624-1634
pubmed: 28947739
Nature. 2018 May;557(7706):503-509
pubmed: 29769716
Clin Chem. 1987 Apr;33(4):572-6
pubmed: 3829393
J Biol Chem. 1979 Sep 10;254(17):8185-93
pubmed: 468819
Carbohydr Res. 1971 Nov;20(1):59-72
pubmed: 5151198
Eur J Biochem. 1982 Jul;125(3):561-6
pubmed: 6749498
Proc Int Conf Intell Syst Mol Biol. 1994;2:28-36
pubmed: 7584402
J Biol Chem. 1995 Jun 16;270(24):14420-9
pubmed: 7782304