Hypertrophic chronic pachymeningitis associated with Epstein-Barr virus reactivation: a case report.
Acyclovir
Corticosteroid treatment
Epstein-Barr virus
Hypertrophic pachymeningitis
Neuroinflammation
Journal
Journal of neurovirology
ISSN: 1538-2443
Titre abrégé: J Neurovirol
Pays: United States
ID NLM: 9508123
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
11
06
2018
accepted:
01
02
2019
revised:
17
12
2018
pubmed:
13
2
2019
medline:
23
9
2020
entrez:
13
2
2019
Statut:
ppublish
Résumé
Hypertrophic pachymeningitis is a rare inflammatory condition characterized by the thickening of the dura mater. We describe a patient who presented with intractable headache and complex cranial nerve palsy. Hypertrophy of the frontal dura was accompanied by pleocytosis and detection of Epstein-Barr virus (EBV) by PCR in cerebrospinal fluid. Clinical symptoms gradually improved after acyclovir and corticosteroid treatment, whereas dural pathology remained unchanged on neuroimaging. This case points at an expansion of the spectrum of neurological manifestations for EBV.
Identifiants
pubmed: 30747332
doi: 10.1007/s13365-019-00731-4
pii: 10.1007/s13365-019-00731-4
doi:
Substances chimiques
Adrenal Cortex Hormones
0
Antiviral Agents
0
Acyclovir
X4HES1O11F
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
426-428Références
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